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Ioxaglic acid
Hexabrix (ioxaglic acid) is a small molecule pharmaceutical. Ioxaglic acid was first approved as Hexabrix on 1985-07-26.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ioxaglate meglumine
+
Ioxaglate sodium
Tradename
Company
Number
Date
Products
HEXABRIXGuerbetN-018905 DISCN1985-07-26
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
V: Various drug classes in atc
— V08: Contrast media
— V08A: X-ray contrast media, iodinated
— V08AB: Watersoluble, nephrotropic, low osmolar x-ray contrast media
— V08AB03: Ioxaglic acid
HCPCS
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Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameIOXAGLIC ACID
INNioxaglic acid
Description
Ioxaglic acid is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position. It has a role as a radioopaque medium. It is an organoiodine compound, a benzenedicarboxamide and a member of benzoic acids.
Classification
Small molecule
Drug classiodine-containing contrast media
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CNC(=O)c1c(I)c(C(=O)NCC(=O)Nc2c(I)c(C(=O)O)c(I)c(C(=O)NCCO)c2I)c(I)c(N(C)C(C)=O)c1I
Identifiers
PDB—
CAS-ID59017-64-0
RxCUI1426458
ChEMBL IDCHEMBL1201291
ChEBI ID31718
PubChem CID3742
DrugBankDB09313
UNII IDZ40X7EI2AF (ChemIDplus, GSRS)
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 310 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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6 adverse events reported
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