Iscalimab
Iscalimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against tumor necrosis factor receptor superfamily member 5.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
13 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sjogren's syndrome | D012859 | EFO_0000699 | M35.0 | — | 2 | — | — | — | 2 |
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | 1 | — | — | — | 1 |
Hidradenitis suppurativa | D017497 | L73.2 | — | 1 | — | — | — | 1 | |
Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | — | 1 | — | — | — | 1 |
Lupus nephritis | D008181 | EFO_0005761 | — | 1 | — | — | — | 1 | |
Graves disease | D006111 | EFO_0004237 | E05.0 | — | 1 | — | — | — | 1 |
Myasthenia gravis | D009157 | EFO_0004991 | G70.0 | — | 1 | — | — | — | 1 |
Kidney transplantation | D016030 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | ISCALIMAB |
INN | iscalimab |
Description | Iscalimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against tumor necrosis factor receptor superfamily member 5. |
Classification | Antibody |
Drug class | monoclonal antibodies |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL4298210 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | 0628T707D0 (ChemIDplus, GSRS) |
Target
Agency Approved
CD40
CD40
Organism
Homo sapiens
Gene name
CD40
Gene synonyms
TNFRSF5
NCBI Gene ID
Protein name
tumor necrosis factor receptor superfamily member 5
Protein synonyms
B cell surface antigen CD40, B cell-associated molecule, B-cell surface antigen CD40, Bp50, CD40, CD40 molecule, TNF receptor superfamily member 5, CD40L receptor, CDw40
Uniprot ID
Mouse ortholog
Cd40 (21939)
tumor necrosis factor receptor superfamily member 5 (Q99NE3)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 117 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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84 adverse events reported
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