Isoleucine
Isoleucine is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target pituitary adenylate cyclase-activating polypeptide type I receptor, vasoactive intestinal polypeptide receptor 1, vasoactive intestinal polypeptide receptor 2, and secretin receptor.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
4 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hyperglycemia | D006943 | HP_0003074 | R73.9 | — | — | — | — | 1 | 1 |
| Diet therapy | D004035 | — | — | — | — | 1 | 1 | ||
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | — | — | 1 | 1 |
| Healthy volunteers/patients | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | ISOLEUCINE |
| INN | isoleucine |
| Description | L-isoleucine is the L-enantiomer of isoleucine. It has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. It is an aspartate family amino acid, a proteinogenic amino acid, an isoleucine and a L-alpha-amino acid. It is a conjugate base of a L-isoleucinium. It is a conjugate acid of a L-isoleucinate. It is an enantiomer of a D-isoleucine. It is a tautomer of a L-isoleucine zwitterion. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC[C@H](C)[C@H](N)C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 73-32-5 |
| RxCUI | 6033 |
| ChEMBL ID | CHEMBL1233584 |
| ChEBI ID | 17191 |
| PubChem CID | 6306 |
| DrugBank | DB00167 |
| UNII ID | 04Y7590D77 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
ADCYAP1R1
ADCYAP1R1
VIPR1
VIPR1
VIPR2
VIPR2
SCTR
SCTR
Organism
Homo sapiens
Gene name
ADCYAP1R1
Gene synonyms
NCBI Gene ID
Protein name
pituitary adenylate cyclase-activating polypeptide type I receptor
Protein synonyms
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I, PACAP receptor 1, PACAP type I receptor, PACAP-R1, pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop, pituitary adenylate cyclase-activating polypeptide type 1 receptor
Uniprot ID
Mouse ortholog
Adcyap1r1 (11517)
pituitary adenylate cyclase-activating polypeptide type I receptor (P70205)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 75,883 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
1 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more