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Lampalizumab
Lampalizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against complement factor D.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Geographic atrophyD057092133——7
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLAMPALIZUMAB
INNlampalizumab
Description
Lampalizumab (humanized mab)
Classification
Antibody
Drug classionotropic non-NMDA (N-methyl D-aspartate) glutamate receptors [AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor) and/or KA (kainite antagonist) receptors]; monoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID1278466-20-8
RxCUI—
ChEMBL IDCHEMBL2109408
ChEBI ID—
PubChem CID—
DrugBankDB11826
UNII IDUWU93Y99R3 (ChemIDplus, GSRS)
Target
Agency Approved
CFD
CFD
Organism
Homo sapiens
Gene name
CFD
Gene synonyms
DF, PFD
NCBI Gene ID
1675
Protein name
complement factor D
Protein synonyms
Adipsin, C3 convertase activator, complement factor D preproprotein, D component of complement (adipsin), Properdin factor D
Uniprot ID
P00746
Mouse ortholog
Cfd (11537)
complement factor D (P03953)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 261 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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