Skip to content
Lazertinib
Lazertinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target tyrosine-protein kinase SYK, vascular endothelial growth factor receptor 2, tyrosine-protein kinase JAK3, and epidermal growth factor receptor.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
35 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD0022894124—221
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lung neoplasmsD008175C34.90—2——13
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—5————5
Hepatic insufficiencyD0485501————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameLAZERTINIB
INNlazertinib
Description
Lazertinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target tyrosine-protein kinase SYK, vascular endothelial growth factor receptor 2, tyrosine-protein kinase JAK3, and epidermal growth factor receptor.
Classification
Small molecule
Drug classtyrosine kinase inhibitors: epidermal growth factor receptor (EGFR) inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C=CC(=O)Nc1cc(Nc2nccc(-n3cc(CN(C)C)c(-c4ccccc4)n3)n2)c(OC)cc1N1CCOCC1
Identifiers
PDB—
CAS-ID1903008-80-9
RxCUI—
ChEMBL IDCHEMBL4558324
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID4A2Y23XK11 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
SYK
SYK
KDR
KDR
JAK3
JAK3
EGFR
EGFR
Organism
Homo sapiens
Gene name
SYK
Gene synonyms
NCBI Gene ID
6850
Protein name
tyrosine-protein kinase SYK
Protein synonyms
p72-Syk, Spleen tyrosine kinase
Uniprot ID
P43405
Mouse ortholog
Syk (20963)
tyrosine-protein kinase SYK (P48025)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 163 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
25 adverse events reported
View more details