Lazucirnon
Lazucirnon is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target C-C chemokine receptor type 3.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Macular degeneration | D008268 | EFO_0001365 | H35.30 | — | 3 | — | — | — | 3 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | 1 | — | — | — | 1 |
| Bullous pemphigoid | D010391 | EFO_0007187 | L12 | — | 1 | — | — | — | 1 |
| Wet macular degeneration | D057135 | EFO_0004683 | — | 1 | — | — | — | 1 | |
| Diabetic retinopathy | D003930 | EFO_0003770 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 4 | — | — | — | — | 4 | ||
| Asthma | D001249 | EFO_0000270 | J45 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | LAZUCIRNON |
| INN | lazucirnon |
| Description | Lazucirnon is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target C-C chemokine receptor type 3. |
| Classification | Small molecule |
| Drug class | Chemokine receptor (CCR) antagonists, not antivirals |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cc(C(=O)N(C)C)cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1 |
Identifiers
| PDB | — |
| CAS-ID | 1251528-23-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3670800 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | R0T9LLR4TN (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
CCR3
CCR3
Organism
Homo sapiens
Gene name
CCR3
Gene synonyms
CMKBR3
NCBI Gene ID
Protein name
C-C chemokine receptor type 3
Protein synonyms
b-chemokine receptor, C-C CKR-3, CC chemokine receptor 3, CCR-3, CD193, chemokine (C-C motif) receptor 3, eosinophil CC chemokine receptor 3, Eosinophil eotaxin receptor
Uniprot ID
Mouse ortholog
Ccr3 (12771)
probable C-C chemokine receptor type 3 (Q8K3M7)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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