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Ghrelin
Ghrelin is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target growth hormone secretagogue receptor type 1.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
44 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C80111——2
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
FrailtyD000073496R53.114———4
AlcoholismD000437EFO_0003829F10.111——13
Peripheral arterial diseaseD058729EFO_000426512———2
AgingD000375GO_0007568R41.8111———1
Traumatic brain injuriesD000070642S06—1———1
Brain concussionD001924S06.0—1———1
Magnetic resonance imagingD008279—1———1
Alcohol drinkingD000428EFO_0004329—1———1
CachexiaD002100HP_0004326R6411———1
Major depressive disorderD003865EFO_0003761F2211———1
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—5———38
ObesityD009765EFO_0001073E66.95———27
Type 2 diabetes mellitusD003924EFO_0001360E111———12
Insulin resistanceD007333EFO_00026141———12
Smoking cessationD016540EFO_00043191————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypopituitarismD007018EFO_0001380E23.0————22
Metabolically benign obesityD000067329————11
Bariatric surgeryD050110————11
MetabolismD008660GO_0008152————11
EpilepsyD004827EFO_0000474G40.9————11
Prader-willi syndromeD011218Orphanet_739Q87.11————11
Fragile x syndromeD005600Q99.2————11
Angelman syndromeD017204Orphanet_72Q93.51————11
Smith-magenis syndromeD058496Orphanet_819Q93.88————11
Feeding and eating disordersD001068F50————11
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameGHRELIN
INNlenomorelin
Description
GHRELIN
Classification
Protein
Drug classprehormones or hormone-release stimulating peptides
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCCCCCCC(=O)OC[C@H](NC(=O)CNC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)O
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL500468
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDUXG268Q86R (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
GHSR
GHSR
Organism
Homo sapiens
Gene name
GHSR
Gene synonyms
NCBI Gene ID
2693
Protein name
growth hormone secretagogue receptor type 1
Protein synonyms
GH-releasing peptide receptor, Ghrelin receptor, GHRP, GHS-R
Uniprot ID
Q92847
Mouse ortholog
Ghsr (208188)
growth hormone secretagogue receptor type 1 (Q99P50)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 31,465 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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