Levosalbutamol
Levosalbutamol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target beta-2 adrenergic receptor.
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Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
1048 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Colorectal neoplasms | D015179 | 59 | 206 | 112 | 3 | 9 | 358 | ||
Stomach neoplasms | D013274 | EFO_0003897 | C16 | 19 | 60 | 15 | 2 | 5 | 92 |
Adenocarcinoma | D000230 | 13 | 35 | 16 | 1 | 1 | 57 | ||
Toxoplasmosis | D014123 | EFO_0007517 | B58 | 1 | — | — | 1 | — | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 44 | 65 | 15 | — | 2 | 106 |
Neoplasms | D009369 | C80 | 54 | 31 | 12 | — | — | 90 | |
Rectal neoplasms | D012004 | 18 | 40 | 12 | — | 1 | 66 | ||
Colonic neoplasms | D003110 | C18 | 13 | 22 | 16 | — | 2 | 47 | |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | C91.0 | 11 | 23 | 16 | — | 2 | 44 | |
Lymphoma | D008223 | C85.9 | 7 | 24 | 10 | — | 4 | 44 | |
Esophageal neoplasms | D004938 | C15 | 10 | 30 | 5 | — | 1 | 40 | |
Leukemia | D007938 | C95 | 3 | 23 | 11 | — | 2 | 39 | |
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 7 | 13 | 7 | — | 4 | 29 |
Hiv infections | D015658 | EFO_0000764 | B20 | 5 | 2 | 8 | — | 8 | 23 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Renal cell carcinoma | D002292 | 8 | 6 | — | — | — | 12 | ||
Myelodysplastic syndromes | D009190 | D46 | 7 | 4 | — | — | — | 10 | |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 7 | 5 | — | — | — | 10 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 4 | 4 | — | — | — | 8 |
Sarcoma | D012509 | 3 | 5 | — | — | — | 8 | ||
Osteosarcoma | D012516 | 3 | 4 | — | — | 2 | 8 | ||
Myeloid leukemia acute | D015470 | C92.0 | 7 | 1 | — | — | — | 7 | |
Non-small-cell lung carcinoma | D002289 | 7 | 2 | — | — | — | 7 | ||
Melanoma | D008545 | 6 | 3 | — | — | — | 7 | ||
Triple negative breast neoplasms | D064726 | 5 | 4 | — | — | — | 6 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Fallopian tube neoplasms | D005185 | 3 | — | — | — | — | 3 | ||
Gastrointestinal stromal tumors | D046152 | EFO_0000505 | C49.A | 3 | — | — | — | — | 3 |
Prostatic neoplasms | D011471 | C61 | 2 | — | — | — | — | 2 | |
Hepatitis c | D006526 | B19.2 | 2 | — | — | — | — | 2 | |
Healthy volunteers/patients | — | 2 | — | — | — | — | 2 | ||
Hematologic neoplasms | D019337 | 1 | — | — | — | — | 1 | ||
Primary myelofibrosis | D055728 | D47.4 | 1 | — | — | — | — | 1 | |
B-cell chronic lymphocytic leukemia | D015451 | C91.1 | 1 | — | — | — | — | 1 | |
Anemia | D000740 | EFO_0004272 | D64.9 | 1 | — | — | — | — | 1 |
Leukemia myeloid chronic atypical bcr-abl negative | D054438 | C92.2 | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Invasive hydatidiform mole | D002820 | D39.2 | — | — | — | — | 1 | 1 | |
Juvenile arthritis | D001171 | EFO_0002609 | M08 | — | — | — | — | 1 | 1 |
Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 1 | 1 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | — | 1 | 1 |
Appetitive behavior | D001070 | — | — | — | — | 1 | 1 | ||
Healthy diet | D000072001 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | LEVOSALBUTAMOL |
INN | levosalbutamol |
Description | (R)-salbutamol is an albuterol. |
Classification | Small molecule |
Drug class | anti-inflammatory agents (salicylic acid derivatives) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC(C)(C)NC[C@H](O)c1ccc(O)c(CO)c1 |
Identifiers
PDB | — |
CAS-ID | 34391-04-3 |
RxCUI | 237159 |
ChEMBL ID | CHEMBL1002 |
ChEBI ID | 8746 |
PubChem CID | 123600 |
DrugBank | DB13139 |
UNII ID | EDN2NBH5SS (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
ADRB2
ADRB2
Organism
Homo sapiens
Gene name
ADRB2
Gene synonyms
ADRB2R, B2AR
NCBI Gene ID
Protein name
beta-2 adrenergic receptor
Protein synonyms
adrenergic, beta-2-, receptor, surface, adrenoceptor beta 2 surface, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, catecholamine receptor
Uniprot ID
Mouse ortholog
Adrb2 (11555)
beta-2 adrenergic receptor (Q8BH38)
Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 132 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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29,028 adverse events reported
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