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Levobupivacaine
Chirocaine (levobupivacaine) is a small molecule pharmaceutical. Levobupivacaine was first approved as Chirocaine on 1999-08-05. It is used to treat pain in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
psychological phenomenaD011579
musculoskeletal and neural physiological phenomenaD055687
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Levobupivacaine hydrochloride
Tradename
Company
Number
Date
Products
CHIROCAINEPurdue PharmaN-020997 DISCN1999-08-05
3 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
painEFO_0003843D010146R52
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N01: Anesthetics
— N01B: Local anesthetics
— N01BB: Amide local anesthetics
— N01BB10: Levobupivacaine
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Macular edemaD008269————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLEVOBUPIVACAINE
INNlevobupivacaine
Description
Levobupivacaine is the (S)-(-)-enantiomer of bupivacaine. It has a role as a local anaesthetic, an adrenergic antagonist, an amphiphile, an EC 3.1.1.8 (cholinesterase) inhibitor and an EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor. It is a conjugate base of a levobupivacaine(1+). It is an enantiomer of a dextrobupivacaine.
Classification
Small molecule
Drug classlocal anesthetics
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C
Identifiers
PDB—
CAS-ID27262-47-1
RxCUI259453
ChEMBL IDCHEMBL1201193
ChEBI ID6149
PubChem CID92253
DrugBankDB01002
UNII IDA5H73K9U3W (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,237 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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216 adverse events reported
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