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Liarozole
Liarozole is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target cytochrome P450 26A1.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lamellar ichthyosisD017490Q80—11——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLIAROZOLE
INNliarozole
Description
Liarozole is a member of benzimidazoles.
Classification
Small molecule
Drug classaromatase inhibitors (imidazole/triazole derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Clc1cccc(C(c2ccc3[nH]cnc3c2)n2ccnc2)c1
Identifiers
PDB—
CAS-ID115575-11-6
RxCUI—
ChEMBL IDCHEMBL389433
ChEBI ID—
PubChem CID60652
DrugBankDB13066
UNII IDK0Q29TGV9Y (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CYP26A1
CYP26A1
Organism
Homo sapiens
Gene name
CYP26A1
Gene synonyms
CYP26, P450RAI1
NCBI Gene ID
1592
Protein name
cytochrome P450 26A1
Protein synonyms
Cytochrome P450 retinoic acid-inactivating 1, cytochrome P450, family 26, subfamily A, polypeptide 1, cytochrome P450, subfamily XXVIA, polypeptide 1, Cytochrome P450RAI, hP450RAI, P450, retinoic acid-inactivating, 1, Retinoic acid 4-hydroxylase, Retinoic acid-metabolizing cytochrome
Uniprot ID
Q5VXI0
Mouse ortholog
Cyp26a1 (13082)
cytochrome P450 26A1 (O55127)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 217 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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