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Lifastuzumab vedotin
Lifastuzumab vedotin is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against sodium-dependent phosphate transport protein 2B.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
No data
ATC Codes
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HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Ovarian neoplasmsD010051EFO_0003893C56—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD0022892————2
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLIFASTUZUMAB VEDOTIN
INNlifastuzumab vedotin
Description
Lifastuzumab vedotin (INN; development code DNIB0600A) is an experimental monoclonal antibody-drug conjugate designed for the treatment of cancer.
Classification
Antibody
Drug classsynthetic analogs of the dolastatin series; monoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID1401812-88-1
RxCUI—
ChEMBL IDCHEMBL4297938
ChEBI ID—
PubChem CID—
DrugBankDB15400
UNII ID7IUT83FK6S (ChemIDplus, GSRS)
Target
Agency Approved
SLC34A2
SLC34A2
Organism
Homo sapiens
Gene name
SLC34A2
Gene synonyms
NCBI Gene ID
10568
Protein name
sodium-dependent phosphate transport protein 2B
Protein synonyms
Na(+)-dependent phosphate cotransporter 2B, Na(+)/Pi cotransporter 2B, NaPi-2b, NaPi3b, Sodium/phosphate cotransporter 2B, solute carrier family 34 (sodium phosphate), member 2, solute carrier family 34 (type II sodium/phosphate cotransporter), member 2, Solute carrier family 34 member 2, type II sodium-dependent phosphate transporter 3b
Uniprot ID
Q9P0V7
Mouse ortholog
Slc34a2 (20531)
sodium-dependent phosphate transport protein 2B (Q9Z290)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 41 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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