Lomefloxacin
Maxaquin (lomefloxacin) is a small molecule pharmaceutical. Lomefloxacin was first approved as Maxaquin on 1992-02-21. It is used to treat bronchitis, escherichia coli infections, klebsiella infections, proteus infections, and pseudomonas infections amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
---|---|
infections | D007239 |
respiratory tract diseases | D012140 |
urogenital diseases | D000091642 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Lomefloxacin hydrochloride
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
MAXAQUIN | Pharmacia & Upjohn | N-020013 DISCN | 1992-02-21 | 1 products |
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
bronchitis | — | D001991 | J40 |
escherichia coli infections | EFO_1001318 | D004927 | B96.20 |
klebsiella infections | EFO_1001353 | D007710 | — |
proteus infections | EFO_1001130 | D011512 | — |
pseudomonas infections | EFO_0001076 | D011552 | — |
staphylococcal infections | — | D013203 | A49.01 |
streptococcal infections | EFO_1001476 | D013290 | — |
urinary tract infections | EFO_0003103 | D014552 | N39.0 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01M: Quinolone antibacterials
— J01MA: Fluoroquinolone antibacterials, systemic
— J01MA07: Lomefloxacin
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AE: Fluoroquinolone antiinfectives, ophthalmologic
— S01AE04: Lomefloxacin
HCPCS
No data
Clinical
Clinical Trials
37 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Opioid-related disorders | D009293 | EFO_0005611 | F11 | 8 | 8 | 4 | — | 1 | 19 |
Marijuana abuse | D002189 | EFO_0007191 | F12 | — | 2 | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | — | 1 | — | — | — | 1 |
Anxiety | D001007 | EFO_0005230 | F41.1 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | 3 | — | — | — | — | 3 | ||
Neonatal abstinence syndrome | D009357 | EFO_0005799 | P96.1 | 2 | — | — | — | — | 2 |
Substance-related disorders | D019966 | EFO_0003890 | F13 | 2 | — | — | — | — | 2 |
Substance withdrawal syndrome | D013375 | EFO_0005800 | 1 | — | — | — | — | 1 | |
Liver failure | D017093 | HP_0001399 | K72.9 | 1 | — | — | — | — | 1 |
Cocaine-related disorders | D019970 | F14 | 1 | — | — | — | — | 1 | |
Heroin dependence | D006556 | EFO_0004240 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | LOMEFLOXACIN |
INN | lomefloxacin |
Description | Lomefloxacin is a fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery. It has a role as an antimicrobial agent, a photosensitizing agent and an antitubercular agent. It is a quinolone, a N-arylpiperazine, a quinolinemonocarboxylic acid, a quinolone antibiotic and a fluoroquinolone antibiotic. |
Classification | Small molecule |
Drug class | antibacterials (quinolone derivatives) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c21 |
Identifiers
PDB | — |
CAS-ID | 98079-51-7 |
RxCUI | 28872 |
ChEMBL ID | CHEMBL561 |
ChEBI ID | 116278 |
PubChem CID | 3948 |
DrugBank | DB00978 |
UNII ID | L6BR2WJD8V (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
No data
Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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123 adverse events reported
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