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Lomefloxacin
Maxaquin (lomefloxacin) is a small molecule pharmaceutical. Lomefloxacin was first approved as Maxaquin on 1992-02-21. It is used to treat bronchitis, escherichia coli infections, klebsiella infections, proteus infections, and pseudomonas infections amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
urogenital diseasesD000091642
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Lomefloxacin hydrochloride
Tradename
Company
Number
Date
Products
MAXAQUINPharmacia & UpjohnN-020013 DISCN1992-02-21
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bronchitisD001991J40
escherichia coli infectionsEFO_1001318D004927B96.20
klebsiella infectionsEFO_1001353D007710
proteus infectionsEFO_1001130D011512
pseudomonas infectionsEFO_0001076D011552
staphylococcal infectionsD013203A49.01
streptococcal infectionsEFO_1001476D013290
urinary tract infectionsEFO_0003103D014552N39.0
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01M: Quinolone antibacterials
J01MA: Fluoroquinolone antibacterials, systemic
J01MA07: Lomefloxacin
S: Sensory organ drugs
S01: Ophthalmologicals
S01A: Antiinfective ophthalmologics
S01AE: Fluoroquinolone antiinfectives, ophthalmologic
S01AE04: Lomefloxacin
HCPCS
No data
Clinical
Clinical Trials
37 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Opioid-related disordersD009293EFO_0005611F11884119
Marijuana abuseD002189EFO_0007191F12212
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Post-traumatic stress disordersD013313EFO_0001358F43.111
AnxietyD001007EFO_0005230F41.111
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients33
Neonatal abstinence syndromeD009357EFO_0005799P96.122
Substance-related disordersD019966EFO_0003890F1322
Substance withdrawal syndromeD013375EFO_000580011
Liver failureD017093HP_0001399K72.911
Cocaine-related disordersD019970F1411
Heroin dependenceD006556EFO_000424011
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLOMEFLOXACIN
INNlomefloxacin
Description
Lomefloxacin is a fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery. It has a role as an antimicrobial agent, a photosensitizing agent and an antitubercular agent. It is a quinolone, a N-arylpiperazine, a quinolinemonocarboxylic acid, a quinolone antibiotic and a fluoroquinolone antibiotic.
Classification
Small molecule
Drug classantibacterials (quinolone derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c21
Identifiers
PDB
CAS-ID98079-51-7
RxCUI28872
ChEMBL IDCHEMBL561
ChEBI ID116278
PubChem CID3948
DrugBankDB00978
UNII IDL6BR2WJD8V (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,391 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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123 adverse events reported
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