Lymecycline
Lymecycline is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
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Indications
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Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Acne vulgaris | D000152 | EFO_0003894 | L70 | — | — | 1 | 1 | — | 2 |
Chlamydia infections | D002690 | EFO_0007205 | A74.9 | — | — | — | 1 | — | 1 |
Urethritis | D014526 | EFO_0003878 | N34 | — | — | — | 1 | — | 1 |
Uterine cervicitis | D002575 | HP_0030160 | N72 | — | — | — | 1 | — | 1 |
Mycoplasma infections | D009175 | — | — | — | 1 | — | 1 |
Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | LYMECYCLINE |
INN | lymecycline |
Description | Lymecycline is a tetracycline-based broad-spectrum antibiotic. It is approximately 5000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by the "active transport" process across the intestinal wall. It has a role as a protein synthesis inhibitor, an antiprotozoal drug, an antibacterial drug and an antimicrobial agent. It is a member of tetracyclines and a tertiary alpha-hydroxy ketone. |
Classification | Small molecule |
Drug class | antibiotics (tetracycline derivatives) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CN(C)[C@@H]1C(O)=C(C(=O)NCNCCCC[C@H](N)C(=O)O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3C[C@@H]12 |
Identifiers
PDB | — |
CAS-ID | 992-21-2 |
RxCUI | 6513 |
ChEMBL ID | CHEMBL2103929 |
ChEBI ID | 59040 |
PubChem CID | 54707177 |
DrugBank | DB00256 |
UNII ID | 7D6EM3S13P (ChemIDplus, GSRS) |
Target
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Variants
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Safety
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125 adverse events reported
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