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Mavorixafor
Mavorixafor is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against C-X-C chemokine receptor type 4.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
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Mock data
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hiv infectionsD015658EFO_0000764B2031———3
Renal cell carcinomaD00229222———2
NeutropeniaD009503D7011———1
Triple negative breast neoplasmsD06472611———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MelanomaD0085451————1
Waldenstrom macroglobulinemiaD008258C88.01————1
Healthy volunteers/patients—1————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMAVORIXAFOR
INNmavorixafor
Description
AMD 070 is an aminoquinoline.
Classification
Small molecule
Drug classCXCR receptor antagonists
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
NCCCCN(Cc1nc2ccccc2[nH]1)[C@H]1CCCc2cccnc21
Identifiers
PDB—
CAS-ID558441-90-0
RxCUI—
ChEMBL IDCHEMBL518924
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID0G9LGB5O2W (ChemIDplus, GSRS)
Target
Agency Approved
CXCR4
CXCR4
Organism
Homo sapiens
Gene name
CXCR4
Gene synonyms
NCBI Gene ID
7852
Protein name
C-X-C chemokine receptor type 4
Protein synonyms
CD184, CD184 antigen, chemokine (C-X-C motif) receptor 4, FB22, Fusin, HM89, LAP-3, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, Lipopolysaccharide-associated protein 3, LPS-associated protein 3, neuropeptide Y receptor Y3, neuropeptide Y3 receptor, NPYRL, SDF-1 receptor, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, Stromal cell-derived factor 1 receptor
Uniprot ID
P61073
Mouse ortholog
Cxcr4 (12767)
C-X-C chemokine receptor type 4 (P70658)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 86 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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