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Reminertant
Reminertant is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target neurotensin receptor type 2 and neurotensin receptor type 1.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lung neoplasmsD008175C34.90—11——1
Small cell lung carcinomaD055752—11——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameREMINERTANT
INNmeclinertant
Description
2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-3-pyrazolyl]-oxomethyl]amino]-2-adamantanecarboxylic acid is a N-acyl-amino acid.
Classification
Small molecule
Drug classtachykinin (neurokinin) receptor antagonists: neurotensin receptor antagonists
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
COc1cccc(OC)c1-c1cc(C(=O)NC2(C(=O)O)C3CC4CC(C3)CC2C4)nn1-c1ccnc2cc(Cl)ccc12
Identifiers
PDB—
CAS-ID146362-70-1
RxCUI—
ChEMBL IDCHEMBL506981
ChEBI ID—
PubChem CID119192
DrugBankDB06455
UNII ID5JBP4SI96H (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
NTSR2
NTSR2
NTSR1
NTSR1
Organism
Homo sapiens
Gene name
NTSR2
Gene synonyms
NCBI Gene ID
23620
Protein name
neurotensin receptor type 2
Protein synonyms
Levocabastine-sensitive neurotensin receptor, neurotensin receptor, type 2, NT-R-2
Uniprot ID
Q8TBH6
Mouse ortholog
Ntsr2 (18217)
neurotensin receptor type 2 (Q8VIF5)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 14 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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