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Mepivacaine
Carbocaine (mepivacaine) is a small molecule pharmaceutical. Mepivacaine was first approved as Carbocaine w/ neo-cobefrin on 1982-01-01. It is used to treat pain in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
psychological phenomenaD011579
musculoskeletal and neural physiological phenomenaD055687
Trade Name
FDA
EMA
Carbocaine (generic drugs available since 1984-10-10, discontinued: Arestocaine, Isocaine, Polocaine)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Levonordefrin
+
Mepivacaine hydrochloride
Tradename
Company
Number
Date
Products
CARBOCAINE W/ NEO-COBEFRINEastman KodakN-012125 DISCN1982-01-01
1 products
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Mepivacaine hydrochloride
Tradename
Company
Number
Date
Products
CARBOCAINEHospiraN-012250 RX1982-01-01
3 products, RLD, RS
Show 1 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
carbocaineANDA2021-07-08
polocaineANDA2023-02-04
polocaine polocaine-mpf ANDA2019-08-12
scandonest 2% lANDA2022-02-10
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
painEFO_0003843D010146R52
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N01: Anesthetics
— N01B: Local anesthetics
— N01BB: Amide local anesthetics
— N01BB03: Mepivacaine
— N01BB53: Mepivacaine, combinations
HCPCS
Code
Description
J0670
Injection, mepivacaine hydrochloride, per 10 ml
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMEPIVACAINE
INNmepivacaine
Description
Mepivacaine is a piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic. It has a role as a local anaesthetic and a drug allergen.
Classification
Small molecule
Drug classlocal anesthetics
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1cccc(C)c1NC(=O)C1CCCCN1C
Identifiers
PDB—
CAS-ID96-88-8
RxCUI—
ChEMBL IDCHEMBL1087
ChEBI ID6759
PubChem CID4062
DrugBankDB00961
UNII IDB6E06QE59J (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,173 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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