Dipyrone
Dipyrone is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Indications
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Agency Specific
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Clinical
Clinical Trials
45 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Postoperative pain | D010149 | G89.18 | — | 2 | 3 | 5 | 5 | 15 | |
| Pain | D010146 | EFO_0003843 | R52 | — | 1 | 1 | 4 | 1 | 7 |
| Cesarean section | D002585 | — | — | — | 3 | — | 3 | ||
| Neuralgia | D009437 | EFO_0009430 | — | — | — | 2 | — | 2 | |
| Pain management | D059408 | — | — | — | 1 | — | 1 | ||
| Anesthesia | D000758 | — | — | — | 1 | — | 1 | ||
| Hip fractures | D006620 | EFO_0003964 | S72.00 | — | — | — | 1 | — | 1 |
| Fever | D005334 | HP_0001945 | R50.9 | — | — | — | 1 | — | 1 |
| Abdominal aortic aneurysm | D017544 | EFO_0004214 | — | — | — | 1 | — | 1 | |
| Atherosclerotic plaque | D058226 | HP_0031678 | I70 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic pain | D059350 | HP_0012532 | — | 1 | 1 | — | — | 2 | |
| Migraine disorders | D008881 | EFO_0003821 | G43 | — | — | 1 | — | — | 1 |
| Spinal cord injuries | D013119 | EFO_1001919 | — | — | 1 | — | — | 1 | |
| Gastroenteritis | D005759 | EFO_1001463 | K52.9 | — | — | 1 | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Drug interactions | D004347 | 2 | — | — | — | — | 2 | ||
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gingival recession | D005889 | K06.0 | — | — | — | — | 3 | 3 | |
| Postoperative nausea and vomiting | D020250 | EFO_0004888 | — | — | — | — | 2 | 2 | |
| Vitreoretinal surgery | D057586 | — | — | — | — | 2 | 2 | ||
| Analgesia | D000698 | — | — | — | — | 2 | 2 | ||
| Tooth abrasion | D014072 | K03.1 | — | — | — | — | 2 | 2 | |
| Intervertebral disc degeneration | D055959 | HP_0008419 | — | — | — | — | 1 | 1 | |
| Platelet aggregation | D010974 | GO_0070527 | — | — | — | — | 1 | 1 | |
| Craniotomy | D003399 | — | — | — | — | 1 | 1 | ||
| Anxiety | D001007 | EFO_0005230 | F41.1 | — | — | — | — | 1 | 1 |
| Chronic pancreatitis | D050500 | EFO_0000342 | K86.1 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | DIPYRONE |
| INN | metamizole sodium |
| Description | Metamizole sodium is an organic sodium salt of antipyrine substituted at C-4 by a methyl(sulfonatomethyl)amino group, commonly used as a powerful analgesic and antipyretic. It has a role as a non-narcotic analgesic, an antirheumatic drug, a peripheral nervous system drug, an antipyretic, a prodrug, a cyclooxygenase 3 inhibitor and an anti-inflammatory agent. It contains a metamizole(1-). |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | Cc1c(N(C)CS(=O)(=O)[O-])c(=O)n(-c2ccccc2)n1C.O.[Na+] |
Identifiers
| PDB | — |
| CAS-ID | 68-89-3 |
| RxCUI | 1537943 |
| ChEMBL ID | CHEMBL3989803 |
| ChEBI ID | — |
| PubChem CID | 522325 |
| DrugBank | DB04817 |
| UNII ID | VSU62Z74ON (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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20,411 adverse events reported
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