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Metaraminol
Aramine (metaraminol) is a small molecule pharmaceutical. Metaraminol was first approved as Metaraminol bitartrate on 1982-01-01. It is used to treat hypotension and shock in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Metaraminol bitartrate
Tradename
Company
Number
Date
Products
ARAMINEMerck KGaAN-009509 DISCN1987-12-22
1 products, RLD
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
hypotensionEFO_0005251D007022I95
shock—D012769R57.1
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C01: Cardiac therapy drugs
— C01C: Cardiac stimulants excl. cardiac glycosides
— C01CA: Adrenergic and dopaminergic cardiac stimulants
— C01CA09: Metaraminol
HCPCS
Code
Description
J0380
Injection, metaraminol bitartrate, per 10 mg
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Substance-related disordersD019966EFO_0003890F13—11——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AlcoholismD000437EFO_0003829F10.1————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMETARAMINOL
INNmetaraminol
Description
Metaraminol is a member of the class of phenylethanolamines that is 2-amino-1-phenylethanol substituted by a methyl group at position 2 and a phenolic hydroxy group at position 1. A sympathomimetic agent , it is used in the treatment of hypotension. It has a role as an alpha-adrenergic agonist, a sympathomimetic agent and a vasoconstrictor agent.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@H](N)[C@H](O)c1cccc(O)c1
Identifiers
PDB—
CAS-ID54-49-9
RxCUI6805
ChEMBL IDCHEMBL1201319
ChEBI ID6794
PubChem CID5906
DrugBankDB00610
UNII ID818U2PZ2EH (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,240 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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293 adverse events reported
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