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Methyclothiazide
Aquatensen, Diutensen-r, Enduron, Enduronyl, Eutron (methyclothiazide) is a small molecule pharmaceutical. Methyclothiazide was first approved as Enduronyl on 1982-01-01. It is used to treat edema, glomerulonephritis, heart failure, hypertension, and liver cirrhosis amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
digestive system diseasesD004066
urogenital diseasesD000091642
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Deserpidine
+
Methyclothiazide
Tradename
Company
Number
Date
Products
ENDURONYLAbbott BiotherapeuticsN-012775 DISCN1982-01-01
1 products
ENDURONYL FORTEAbbott BiotherapeuticsN-012775 DISCN1982-01-01
1 products
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Methyclothiazide
Tradename
Company
Number
Date
Products
ENDURONAbbVieN-012524 DISCN1982-01-01
2 products, RLD
AQUATENSENMedpointe Pharm HlcN-017364 DISCN1982-01-01
1 products
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Methyclothiazide
+
Pargyline hydrochloride
Tradename
Company
Number
Date
Products
EUTRONAbbott BiotherapeuticsN-016047 DISCN1982-01-01
1 products
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Methyclothiazide
+
Reserpine
Tradename
Company
Number
Date
Products
DIUTENSEN-RMedpointe Pharm HlcN-012708 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
edema—D004487R60.9
glomerulonephritis—D005921N05
heart failureEFO_0003144D006333I50
hypertensionEFO_0000537D006973I10
liver cirrhosisEFO_0001422D008103K74.0
nephrotic syndromeEFO_0004255D009404N04
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C03: Diuretics
— C03A: Low-ceiling diuretics, thiazides
— C03AA: Thiazides, plain
— C03AA08: Methyclothiazide
— C03AB: Thiazides and potassium in combination
— C03AB08: Methyclothiazide and potassium
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
EpilepsyD004827EFO_0000474G40.9————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMETHYCLOTHIAZIDE
INNmethyclothiazide
Description
Methyclothiazide is a benzothiadiazine.
Classification
Small molecule
Drug classdiuretics (thiazide derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CN1C(CCl)Nc2cc(Cl)c(S(N)(=O)=O)cc2S1(=O)=O
Identifiers
PDB—
CAS-ID135-07-9
RxCUI6860
ChEMBL IDCHEMBL1577
ChEBI ID6847
PubChem CID4121
DrugBankDB00232
UNII IDL3H46UAC61 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 193 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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102 adverse events reported
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