Methyl salicylate
Salonpas (methyl salicylate) is a small molecule pharmaceutical. Methyl salicylate was first approved as Salonpas on 2008-02-20. It is used to treat acute pain, arthritis, back pain, contusions, and inflammation amongst others in the USA. It is known to target transient receptor potential cation channel subfamily A member 1.
Download report
Favorite
Commercial
Trade Name
FDA
EMA
Combinations
Salonpas
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Menthol
+
Methyl salicylate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| SALONPAS | HISAMITSU PHARM CO | N-022029 OTC | 2008-02-20 | 2 products, RLD, RS |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| acute pain | — | D059787 | R52 |
| arthritis | EFO_0005856 | D001168 | M05-M14 |
| back pain | HP_0003418 | D001416 | M54 |
| contusions | — | D003288 | T14.8 |
| inflammation | MP_0001845 | D007249 | — |
| muscle cramp | HP_0003394 | D009120 | — |
| sprains and strains | — | D013180 | — |
Agency Specific
FDA
EMA
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
42 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acne vulgaris | D000152 | EFO_0003894 | L70 | — | 2 | — | — | 1 | 3 |
| Photochemotherapy | D010778 | 1 | 1 | — | — | — | 1 | ||
| Uterine cervical dysplasia | D002578 | EFO_1000910 | N87 | 1 | 1 | — | — | — | 1 |
| Squamous intraepithelial lesions | D000081483 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 | ||
| Pain | D010146 | EFO_0003843 | R52 | 1 | — | — | — | — | 1 |
| Skin neoplasms | D012878 | EFO_0004198 | C44 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leg ulcer | D007871 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | METHYL SALICYLATE |
| INN | — |
| Description | Methyl salicylate is a benzoate ester that is the methyl ester of salicylic acid. It has a role as a flavouring agent, a metabolite and an insect attractant. It is a benzoate ester, a member of salicylates and a methyl ester. It is functionally related to a salicylic acid. |
| Classification | Small molecule |
| Drug class | anti-inflammatory agents (salicylic acid derivatives) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | COC(=O)c1ccccc1O |
Identifiers
| PDB | — |
| CAS-ID | 119-36-8 |
| RxCUI | 29787 |
| ChEMBL ID | CHEMBL108545 |
| ChEBI ID | 31832 |
| PubChem CID | 4133 |
| DrugBank | DB09543 |
| UNII ID | — |
Target
Agency Approved
No data
Alternate
TRPA1
TRPA1
Organism
Homo sapiens
Gene name
TRPA1
Gene synonyms
ANKTM1
NCBI Gene ID
Protein name
transient receptor potential cation channel subfamily A member 1
Protein synonyms
ankyrin-like with transmembrane domains 1, Ankyrin-like with transmembrane domains protein 1, p120, Transformation-sensitive protein p120, Wasabi receptor
Uniprot ID
Mouse ortholog
Trpa1 (277328)
transient receptor potential cation channel subfamily A member 1 (Q8BLA8)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 5,429 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
87 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more