Skip to content
Mexitil, Namuscla(mexiletine hydrochloride)
Mexitil, Namuscla (mexiletine hydrochloride) is a small molecule pharmaceutical. Mexiletine hydrochloride was first approved as Mexitil on 1985-12-30. It is used to treat cardiac arrhythmias, diabetic neuropathies, ventricular fibrillation, and ventricular premature complexes in the USA. It has been approved in Europe to treat myotonic disorders.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
musculoskeletal diseasesD009140
nervous system diseasesD009422
cardiovascular diseasesD002318
endocrine system diseasesD004700
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Mexiletine hydrochloride
Tradename
Company
Number
Date
Products
MEXITILBoehringer IngelheimN-018873 DISCN1985-12-30
3 products, RLD
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
mexiletine hydrochlorideANDA2023-06-16
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
cardiac arrhythmiasEFO_0004269D001145I49.9
diabetic neuropathiesEFO_1000783D003929—
ventricular fibrillationEFO_0004287D014693I49.01
ventricular premature complexes—D018879I49.3
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C01: Cardiac therapy drugs
— C01B: Antiarrhythmics, class i and iii
— C01BB: Antiarrhythmics, class ib
— C01BB02: Mexiletine
HCPCS
No data
Clinical
Clinical Trials
24 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Amyotrophic lateral sclerosisD000690EFO_0000253G12.21—2—1—3
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Myotonic dystrophyD009223G71.11—22—15
Myotonic disordersD020967Orphanet_606G71.1——1—12
Cardiovascular diseasesD002318EFO_0000319I98——2——2
Heart diseasesD006331EFO_0003777I51.9——2——2
Cardiac arrhythmiasD001145EFO_0004269I49.9——2——2
Ventricular fibrillationD014693EFO_0004287I49.01——2——2
Myocardial infarctionD009203EFO_0000612I21——1——1
Heart arrestD006323EFO_0009492I46——1——1
Myotonia congenitaD009224G71.12——1——1
Ventricular tachycardiaD017180I47.2——1——1
Show 4 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Charcot-marie-tooth diseaseD002607G60.0—1———1
Hiv infectionsD015658EFO_0000764B20—1———1
Peripheral nervous system diseasesD010523G64—1———1
MyotoniaD009222—1———1
Surgical amputationD000671—1———1
Chronic painD059350HP_0012532—1———1
DystoniaD004421HP_0001332G24—1———1
BlepharospasmD001764G24.5—1———1
SpasmD013035M62.83—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PharmacokineticsD0105991————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameMEXILETINE HYDROCHLORIDE
INNmexiletine
Description
Mexiletine is an aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol. It has a role as an anti-arrhythmia drug. It is an aromatic ether and a primary amino compound.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1cccc(C)c1OCC(C)N.Cl
Identifiers
PDB—
CAS-ID5370-01-4
RxCUI—
ChEMBL IDCHEMBL1200606
ChEBI ID6917
PubChem CID4178
DrugBankDB00379
UNII ID1U511HHV4Z (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 3,223 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
722 adverse events reported
View more details