Skip to content
Minodronic acid
Minodronic acid is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target geranylgeranyl pyrophosphate synthase and farnesyl pyrophosphate synthase.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Postmenopausal osteoporosisD015663EFO_00038541——1—2
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OsteoporosisD010024EFO_0003882M81.0215——7
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bone diseasesD001847M89.91————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameMINODRONIC ACID
INNminodronic acid
Description
Minodronic acid is a third-generation bisphosphonate drug. It is approved for use in Japan for the treatment of osteoporosis. Its mechanism of action involves inhibition of farnesyl pyrophosphate synthase activity.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=P(O)(O)C(O)(Cc1cnc2ccccn12)P(=O)(O)O
Identifiers
PDB3ICK
CAS-ID180064-38-4
RxCUI—
ChEMBL IDCHEMBL319144
ChEBI ID—
PubChem CID130956
DrugBankDB06548
UNII ID40SGR63TGL (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
GGPS1
GGPS1
FDPS
FDPS
Organism
Homo sapiens
Gene name
GGPS1
Gene synonyms
NCBI Gene ID
9453
Protein name
geranylgeranyl pyrophosphate synthase
Protein synonyms
(2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, GGPP synthase, GGPPSase
Uniprot ID
Q6NW19
Mouse ortholog
Ggps1 (14593)
geranylgeranyl pyrophosphate synthase (Q9WTN0)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 161 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
108 adverse events reported
View more details