Mirikizumab
Mirikizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target interleukin-23 subunit alpha.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
33 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | 2 | 5 | — | — | 7 |
| Psoriasis | D011565 | EFO_0000676 | L40 | 2 | 1 | 3 | — | — | 6 |
| Crohn disease | D003424 | EFO_0000384 | K50 | — | 1 | 4 | — | — | 5 |
| Inflammatory bowel diseases | D015212 | EFO_0003767 | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 14 | — | — | — | — | 14 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | MIRIKIZUMAB |
| INN | mirikizumab |
| Description | Mirikizumab (INN; trade name Omvoh; development code LY3074828) is a human monoclonal antibody designed for the treatment of immune-mediated diseases psoriasis and ulcerative colitis.
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| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL3990014 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | Z7HVY03PHP (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
IL23A
IL23A
Organism
Homo sapiens
Gene name
IL23A
Gene synonyms
SGRF
NCBI Gene ID
Protein name
interleukin-23 subunit alpha
Protein synonyms
IL-23 subunit alpha, IL-23-A, IL-23p19, interleukin 23 p19 subunit, interleukin 23, alpha subunit p19, Interleukin-23 subunit p19, interleukin-six, G-CSF related factor, JKA3 induced upon T-cell activation
Uniprot ID
Mouse ortholog
Il23a (83430)
interleukin-23 subunit alpha (Q9EQ14)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 205 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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