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Mocetinostat
Mocetinostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target histone deacetylase 2, histone deacetylase 3, and histone deacetylase 1.
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SARS-CoV-2 Interaction
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
23 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Myelodysplastic syndromesD009190D46446
Myeloid leukemia acuteD015470C92.0133
Hodgkin diseaseD006689C81133
NeoplasmsD009369C80323
Non-hodgkin lymphomaD008228C85.9112
Non-small-cell lung carcinomaD002289112
LymphomaD008223C85.9122
LeiomyosarcomaD00789011
Large b-cell lymphoma diffuseD016403C83.3111
Urologic neoplasmsD014571C64-C6811
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lung neoplasmsD008175C34.9022
LeukemiaD007938C9522
Squamous cell carcinoma of head and neckD00007719511
Squamous cell carcinomaD00229411
Prostatic neoplasmsD011471C6111
Breast neoplasmsD001943EFO_0003869C5011
Stomach neoplasmsD013274EFO_0003897C1611
MelanomaD00854511
RhabdomyosarcomaD01220811
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMOCETINOSTAT
INNmocetinostat
Description
N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]benzamide is a member of benzamides.
Classification
Small molecule
Drug classenzyme inhibitors: histone deacetylase inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cccnc3)n2)cc1
Identifiers
PDB
CAS-ID726169-73-9
RxCUI
ChEMBL IDCHEMBL272980
ChEBI ID
PubChem CID9865515
DrugBankDB11830
UNII IDA6GWB8T96J (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
HDAC2
HDAC2
HDAC3
HDAC3
HDAC1
HDAC1
Organism
Homo sapiens
Gene name
HDAC2
Gene synonyms
NCBI Gene ID
Protein name
histone deacetylase 2
Protein synonyms
Protein deacylase HDAC2, transcriptional regulator homolog RPD3, YY1-associated factor 1
Uniprot ID
Mouse ortholog
Hdac2 (15182)
histone deacetylase 2 (P70288)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 900 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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7 adverse events reported
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