Skip to content
Moclobemide
Moclobemide is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against amine oxidase [flavin-containing] A. In addition, it is known to target amine oxidase [flavin-containing] B.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N06: Psychoanaleptics
— N06A: Antidepressants
— N06AG: Mao a inhibitors, antidepressant drugs
— N06AG02: Moclobemide
HCPCS
No data
Clinical
Clinical Trials
4 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DementiaD003704F03——1——1
Psychophysiologic disordersD011602F45.9——1——1
SchizophreniaD012559EFO_0000692F20——1——1
DepressionD003863F33.9——1——1
Anxiety disordersD001008EFO_0006788F41.1——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Tobacco use disorderD014029F17—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameMOCLOBEMIDE
INNmoclobemide
Description
Moclobemide is a member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression. It has a role as a xenobiotic, an environmental contaminant and an antidepressant. It is a member of monochlorobenzenes, a member of morpholines and a member of benzamides.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=C(NCCN1CCOCC1)c1ccc(Cl)cc1
Identifiers
PDB—
CAS-ID71320-77-9
RxCUI30121
ChEMBL IDCHEMBL86304
ChEBI ID83531
PubChem CID4235
DrugBankDB01171
UNII IDPJ0Y7AZB63 (ChemIDplus, GSRS)
Target
Agency Approved
MAOA
MAOA
Organism
Homo sapiens
Gene name
MAOA
Gene synonyms
NCBI Gene ID
4128
Protein name
amine oxidase [flavin-containing] A
Protein synonyms
MAO-A, Monoamine oxidase type A
Uniprot ID
Q16426
Mouse ortholog
Maoa (17161)
amine oxidase [flavin-containing] A (Q8K0Z8)
Alternate
MAOB
MAOB
Organism
Homo sapiens
Gene name
MAOB
Gene synonyms
NCBI Gene ID
4129
Protein name
amine oxidase [flavin-containing] B
Protein synonyms
adrenalin oxidase, MAO, brain, MAO, platelet, MAO-B, Monoamine oxidase type B, tyramine oxidase
Uniprot ID
Q7Z6S2
Mouse ortholog
Maob (109731)
amine oxidase [flavin-containing] B (Q8C0B2)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 1,915 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
381 adverse events reported
View more details