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Moexipril
Uniretic, Univasc (moexipril) is a small molecule pharmaceutical. Moexipril was first approved as Univasc on 1995-04-19. It is used to treat diabetic nephropathies, heart failure, hypertension, and left ventricular dysfunction in the USA. The pharmaceutical is active against angiotensin-converting enzyme.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
urogenital diseasesD000091642
cardiovascular diseasesD002318
endocrine system diseasesD004700
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Hydrochlorothiazide
+
Moexipril hydrochloride
Tradename
Company
Number
Date
Products
UNIRETICUCBN-020729 DISCN1997-06-27
3 products
Hide discontinued
Moexipril hydrochloride
Tradename
Company
Number
Date
Products
UNIVASCUCBN-020312 DISCN1995-04-19
2 products
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
moexipril hydrochlorideANDA2021-08-18
univascNew Drug Application2016-02-23
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
diabetic nephropathiesEFO_0000401D003928
heart failureEFO_0003144D006333I50
hypertensionEFO_0000537D006973I10
left ventricular dysfunctionD018487
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
C09: Agents acting on the renin-angiotensin system
C09A: Ace inhibitors, plain
C09AA: Ace inhibitors, plain
C09AA13: Moexipril
C09B: Ace inhibitors, combinations
C09BA: Ace inhibitors and diuretics
C09BA13: Moexipril and diuretics
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic hyperplasiaD011470EFO_0000284N4011
Retinal diseasesD012164HP_0000479H35.911
IntubationD00744011
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Liver diseasesD008107EFO_0001421K70-K7711
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SexD012723PATO_000189411
Muscle relaxationD00912611
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Neuromuscular blockadeD01914811
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMOEXIPRIL
INNmoexipril
Description
Moexipril is a peptide.
Classification
Small molecule
Drug classantihypertensives (ACE inhibitors)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2cc(OC)c(OC)cc2C[C@H]1C(=O)O
Identifiers
PDB
CAS-ID103775-10-6
RxCUI30131
ChEMBL IDCHEMBL1165
ChEBI ID6960
PubChem CID91270
DrugBankDB00691
UNII IDWT87C52TJZ (ChemIDplus, GSRS)
Target
Agency Approved
ACE
ACE
Organism
Homo sapiens
Gene name
ACE
Gene synonyms
DCP, DCP1
NCBI Gene ID
Protein name
angiotensin-converting enzyme
Protein synonyms
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, carboxycathepsin, CD143, CD143 antigen, dipeptidyl carboxypeptidase 1, Dipeptidyl carboxypeptidase I, Kininase II, peptidase P
Uniprot ID
Mouse ortholog
Ace (11421)
angiotensin-converting enzyme (P09470)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 344 documents
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Safety
Black-box Warning
Black-box warning for: Univasc
Adverse Events
Top Adverse Reactions
Mock data
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132 adverse events reported
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