Skip to content
Molindone
Moban (molindone) is a small molecule pharmaceutical. Molindone was first approved as Moban on 1982-01-01. It is used to treat psychotic disorders, schizophrenia, and schizophrenia spectrum and other psychotic disorders in the USA. The pharmaceutical is active against 5-hydroxytryptamine receptor 2A. In addition, it is known to target histamine H1 receptor.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
mental disordersD001523
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Molindone hydrochloride
Tradename
Company
Number
Date
Products
MOBANEndoN-017938 DISCN1982-01-01
1 products
MOBANStrides Pharma GlobalN-017111 DISCN1982-01-01
8 products, RLD
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
molindone hydrochlorideANDA2019-10-31
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
psychotic disorders—D011618F20.81
schizophreniaEFO_0000692D012559F20
schizophrenia spectrum and other psychotic disorders—D019967—
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N05: Psycholeptics
— N05A: Antipsychotics
— N05AE: Indole derivatives, antipsychotic
— N05AE02: Molindone
HCPCS
No data
Clinical
Clinical Trials
5 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Biliary liver cirrhosisD008105K74.3—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—4————4
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameMOLINDONE
INNmolindone
Description
Molindone is a member of indoles.
Classification
Small molecule
Drug classTypical antipsychotic
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCc1c(C)[nH]c2c1C(=O)C(CN1CCOCC1)CC2
Identifiers
PDB—
CAS-ID7416-34-4
RxCUI—
ChEMBL IDCHEMBL460
ChEBI ID6965
PubChem CID23897
DrugBankDB01618
UNII IDRT3Y3QMF8N (ChemIDplus, GSRS)
Target
Agency Approved
HTR2A
HTR2A
Organism
Homo sapiens
Gene name
HTR2A
Gene synonyms
HTR2
NCBI Gene ID
3356
Protein name
5-hydroxytryptamine receptor 2A
Protein synonyms
5-HT2 receptor, 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled, serotonin 5-HT-2A receptor, Serotonin receptor 2A
Uniprot ID
Q5T8C0
Mouse ortholog
Htr2a (15558)
5-hydroxytryptamine receptor 2A (P35363)
Alternate
HRH1
HRH1
Organism
Homo sapiens
Gene name
HRH1
Gene synonyms
NCBI Gene ID
3269
Protein name
histamine H1 receptor
Protein synonyms
histamine receptor, subclass H1
Uniprot ID
Q6P9E5
Mouse ortholog
Hrh1 (15465)
histamine H1 receptor (Q91XN3)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 345 documents
View more details
Safety
Black-box Warning
Black-box warning for: Molindone hydrochloride
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
94 adverse events reported
View more details