Napabucasin
Napabucasin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
25 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | 2 | 3 | 3 | — | — | 7 | ||
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | 1 | — | — | 2 |
| Non-small-cell lung carcinoma | D002289 | 1 | 1 | 1 | — | — | 2 | ||
| Pancreatic ductal carcinoma | D021441 | — | — | 1 | — | — | 1 | ||
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | C80 | 3 | 1 | — | — | — | 3 | |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 2 | 1 | — | — | — | 2 |
| Glioblastoma | D005909 | EFO_0000515 | 1 | 1 | — | — | — | 1 | |
| Gastrointestinal neoplasms | D005770 | C26.9 | 1 | 1 | — | — | — | 1 | |
| Malignant mesothelioma | D000086002 | 1 | 1 | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | NAPABUCASIN |
| INN | napabucasin |
| Description | Napabucasin is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)c1cc2c(o1)C(=O)c1ccccc1C2=O |
Identifiers
| PDB | — |
| CAS-ID | 83280-65-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL64130 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | Z1HHM49K7O (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 473 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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72 adverse events reported
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