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Navoximod
Navoximod is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C803————3
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameNAVOXIMOD
INNnavoximod
Description
Navoximod is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase.
Classification
Small molecule
Drug classimmunomodulators
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O[C@H](C[C@H]1c2c(F)cccc2-c2cncn21)[C@H]1CC[C@H](O)CC1
Identifiers
PDB—
CAS-ID1402836-86-5
RxCUI—
ChEMBL IDCHEMBL3989951
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID926SHL95NC (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
IDO1
IDO1
TDO2
TDO2
Organism
Homo sapiens
Gene name
IDO1
Gene synonyms
IDO, INDO
NCBI Gene ID
3620
Protein name
indoleamine 2,3-dioxygenase 1
Protein synonyms
indolamine 2,3 dioxygenase, indole 2,3-dioxygenase, Indoleamine-pyrrole 2,3-dioxygenase
Uniprot ID
Q540B4
Mouse ortholog
Ido1 (15930)
indoleamine 2,3-dioxygenase 1 (P28776)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 246 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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12 adverse events reported
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