Nefopam
Nefopam is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Therapeutic Areas
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Trade Name
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
40 clinical trials
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | — | — | 1 | — | 2 | 3 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | 1 | — | 1 | 2 |
| Pancreatitis | D010195 | EFO_0000278 | K85 | — | — | 1 | — | — | 1 |
| Cholecystectomy | D002763 | — | — | 1 | — | — | 1 | ||
| Acute pain | D059787 | R52 | — | — | 1 | — | — | 1 | |
| Wound infection | D014946 | — | 1 | 1 | — | — | 1 | ||
| Laparotomy | D007813 | — | 1 | 1 | — | — | 1 | ||
| Dyspnea | D004417 | HP_0002094 | R06.0 | — | — | 1 | — | — | 1 |
| Chronic disease | D002908 | — | 1 | 1 | — | — | 1 | ||
| Hyperalgesia | D006930 | — | 1 | 1 | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 3 | — | — | — | — | 3 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Retinal neoplasms | D019572 | C69.2 | — | — | — | — | 1 | 1 | |
| Kidney transplantation | D016030 | — | — | — | — | 1 | 1 | ||
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | — | — | 1 | 1 |
| Colonic neoplasms | D003110 | C18 | — | — | — | — | 1 | 1 | |
| Colonic diverticulosis | D043963 | K57.30 | — | — | — | — | 1 | 1 | |
| Hypothermia | D007035 | HP_0002045 | T68 | — | — | — | — | 1 | 1 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | — | — | — | — | 1 | 1 |
| Thyroidectomy | D013965 | — | — | — | — | 1 | 1 | ||
| Orthognathic surgery | D057909 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | NEFOPAM |
| INN | nefopam |
| Description | 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine is a member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively. It is a benzoxazocine and a tertiary amino compound. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CN1CCOC(c2ccccc2)c2ccccc2C1 |
Identifiers
| PDB | — |
| CAS-ID | 110011-82-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL465026 |
| ChEBI ID | 88318 |
| PubChem CID | 4450 |
| DrugBank | — |
| UNII ID | 4UP8060B7J (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Trends
PubMed Central
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Additional graphs summarizing 829 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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1,706 adverse events reported
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