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Nemolizumab
Nemolizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against interleukin-31 receptor subunit alpha.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
17 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Atopic dermatitisD003876EFO_0000274L20—64——10
PrurigoD011536L28.2——4——4
Chronic renal insufficiencyD051436N18—11——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Systemic sclerodermaD012595EFO_0000717M34—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—1————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameNEMOLIZUMAB
INNnemolizumab
Description
Nemolizumab is an experimental drug for the treatment of itching in people with atopic dermatitis. It is a monoclonal antibody that blocks the interleukin-31 receptor A. Results of a Phase II clinical trial were published in March 2017.
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL4297794
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDGN465U8B72 (ChemIDplus, GSRS)
Target
Agency Approved
IL31RA
IL31RA
Organism
Homo sapiens
Gene name
IL31RA
Gene synonyms
CRL3, GPL
NCBI Gene ID
133396
Protein name
interleukin-31 receptor subunit alpha
Protein synonyms
class I cytokine receptor, Cytokine receptor-like 3, GLM-R, Gp130-like monocyte receptor, Gp130-like receptor, hGLM-R, IL-31 receptor subunit alpha, IL-31R subunit alpha, soluble type I cytokine receptor CRL3, ZcytoR17
Uniprot ID
Q8NI17
Mouse ortholog
Il31ra (218624)
interleukin-31 receptor subunit alpha (Q8R501)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 328 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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