Netilmicin
Netromycin (netilmicin) is a small molecule pharmaceutical. Netilmicin was first approved as Netromycin on 1983-02-28. It is used to treat bacterial infections, gram-negative bacterial infections, and staphylococcal infections in the USA.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Netilmicin sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| NETROMYCIN | Merck Sharp & Dohme | N-050544 DISCN | 1983-02-28 | 3 products |
Hide discontinued
Labels
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01G: Aminoglycoside antibacterials
— J01GB: Other aminoglycosides in atc
— J01GB07: Netilmicin
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA23: Netilmicin
HCPCS
No data
Clinical
Clinical Trials
108 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ventilator-associated pneumonia | D053717 | EFO_1001865 | J95.851 | — | 2 | 8 | 1 | 1 | 10 |
| Infections | D007239 | EFO_0000544 | — | — | 4 | 1 | 1 | 6 | |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 1 | 1 | 2 | — | 4 |
| Colorectal neoplasms | D015179 | 1 | 1 | — | 1 | 1 | 4 | ||
| Dental pulp necrosis | D003790 | K04.1 | 3 | — | — | 1 | — | 4 | |
| Acinetobacter infections | D000151 | EFO_1000792 | — | — | — | 1 | 2 | 3 | |
| Bacterial infections | D001424 | A49 | — | — | 1 | 1 | 1 | 3 | |
| Critical illness | D016638 | 1 | — | — | 1 | — | 2 | ||
| Communicable diseases | D003141 | — | — | 1 | 1 | — | 2 | ||
| Gram-negative bacterial infections | D016905 | — | — | — | 2 | — | 2 |
Show 7 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bacteremia | D016470 | EFO_0003033 | R78.81 | — | 1 | 2 | — | 1 | 3 |
| Pneumonia | D011014 | EFO_0003106 | J18 | — | — | 2 | — | 1 | 3 |
| Healthy volunteers/patients | — | — | — | 3 | — | — | 3 | ||
| Sepsis | D018805 | A41.9 | — | — | 1 | — | 1 | 2 | |
| Iatrogenic disease | D007049 | — | — | 1 | — | — | 1 | ||
| Drug-related side effects and adverse reactions | D064420 | T88.7 | — | — | 1 | — | — | 1 | |
| Bronchitis | D001991 | J40 | — | — | 1 | — | — | 1 | |
| Pyelonephritis | D011704 | EFO_1001141 | N10-N16 | — | — | 1 | — | — | 1 |
| Healthcare-associated pneumonia | D000077299 | — | — | 1 | — | — | 1 | ||
| Bacterial pneumonia | D018410 | EFO_1001272 | J15.9 | — | — | 1 | — | — | 1 |
Show 6 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Crohn disease | D003424 | EFO_0000384 | K50 | — | 2 | — | — | — | 2 |
| Heart failure | D006333 | EFO_0003144 | I50 | — | 1 | — | — | 1 | 2 |
| Pseudomonas aeruginosa | D011550 | NCBITaxon_287 | — | 1 | — | — | — | 1 | |
| Weight loss | D015431 | HP_0001824 | — | 1 | — | — | — | 1 | |
| Cachexia | D002100 | HP_0004326 | R64 | — | 1 | — | — | — | 1 |
| Anorexia | D000855 | HP_0002039 | R63.0 | — | 1 | — | — | — | 1 |
| Rectal neoplasms | D012004 | — | 1 | — | — | — | 1 | ||
| Anastomotic leak | D057868 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Inflammatory bowel diseases | D015212 | EFO_0003767 | 1 | — | — | — | 1 | 2 | |
| Hepatic encephalopathy | D006501 | K72.91 | 1 | — | — | — | 1 | 2 | |
| Surgical wound infection | D013530 | 1 | — | — | — | 1 | 2 | ||
| Gram-negative bacteria | D006090 | 1 | — | — | — | — | 1 | ||
| Retinoblastoma | D012175 | 1 | — | — | — | — | 1 | ||
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | — | — | — | — | 1 |
| Neoplasms | D009369 | C80 | 1 | — | — | — | — | 1 | |
| Asymptomatic diseases | D058070 | 1 | — | — | — | — | 1 | ||
| Diverticulitis | D004238 | EFO_1001460 | K57 | 1 | — | — | — | — | 1 |
| Regeneration | D012038 | 1 | — | — | — | — | 1 |
Show 1 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | — | — | — | 1 | 1 |
| Corneal diseases | D003316 | H18.9 | — | — | — | — | 1 | 1 | |
| Gestational diabetes | D016640 | HP_0009800 | O24.4 | — | — | — | — | 1 | 1 |
| Necrotizing enterocolitis | D020345 | EFO_0003928 | K55.3 | — | — | — | — | 1 | 1 |
| Hirschsprung disease | D006627 | Q43.1 | — | — | — | — | 1 | 1 | |
| Colostomy | D003125 | — | — | — | — | 1 | 1 | ||
| Meconium ileus | D000074270 | P76.0 | — | — | — | — | 1 | 1 | |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 1 | 1 |
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | — | — | — | 1 | 1 |
| Postoperative complications | D011183 | — | — | — | — | 1 | 1 |
Show 19 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | NETILMICIN |
| INN | netilmicin |
| Description | Netilmicin (1-N-ethylsisomicin) is a semisynthetic aminoglycoside antibiotic, and a derivative of sisomicin, produced by Micromonospora inyoensis. Aminoglycoside antibiotics have the ability to kill a wide variety of bacteria. Netilmicin is not absorbed from the gut and is therefore only given by injection or infusion. It is only used in the treatment of serious infections particularly those resistant to gentamicin.
|
| Classification | Small molecule |
| Drug class | antibiotics (Micromonospora strains) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@](C)(O)[C@H](NC)[C@H]1O |
Identifiers
| PDB | — |
| CAS-ID | 56391-56-1 |
| RxCUI | 7337 |
| ChEMBL ID | CHEMBL1572 |
| ChEBI ID | — |
| PubChem CID | 441306 |
| DrugBank | DB00955 |
| UNII ID | 4O5J85GJJB (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 3,636 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
3,681 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more