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Olcegepant
Olcegepant is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target calcitonin receptor and calcitonin gene-related peptide type 1 receptor.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
7 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Migraine disordersD008881EFO_0003821G4311
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients66
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOLCEGEPANT
INNolcegepant
Description
Olcegepant (INN, code name BIBN-4096BS) is a calcitonin gene-related peptide receptor antagonist being studied as a potential treatment for migraines.
Classification
Small molecule
Drug classcalcitonin gene-related peptide receptor antagonists
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
NCCCC[C@H](NC(=O)[C@@H](Cc1cc(Br)c(O)c(Br)c1)NC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1)C(=O)N1CCN(c2ccncc2)CC1
Identifiers
PDB
CAS-ID204697-65-4
RxCUI
ChEMBL IDCHEMBL207197
ChEBI ID
PubChem CID6918509
DrugBankDB04869
UNII IDWOA5J8TX6M (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CALCR
CALCR
CALCRL
CALCRL
Organism
Homo sapiens
Gene name
CALCR
Gene synonyms
NCBI Gene ID
Protein name
calcitonin receptor
Protein synonyms
Uniprot ID
Mouse ortholog
Calcr (12311)
calcitonin receptor (Q60755)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 330 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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