Omecamtiv mecarbil
Omecamtiv mecarbil is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Agency Specific
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Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | EFO_0003144 | I50 | 2 | 8 | 3 | — | — | 13 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Left ventricular dysfunction | D018487 | — | 1 | — | — | — | 1 | ||
| Stroke volume | D013318 | — | 1 | — | — | — | 1 | ||
| Pharmacokinetics | D010599 | — | 1 | — | — | — | 1 | ||
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | 1 | — | — | — | 1 |
| Angina pectoris | D000787 | EFO_0003913 | I20 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | OMECAMTIV MECARBIL |
| INN | omecamtiv mecarbil |
| Description | Omecamtiv mecarbil is a member of ureas. |
| Classification | Small molecule |
| Drug class | cardiac myosin activator |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | COC(=O)N1CCN(Cc2cccc(NC(=O)Nc3ccc(C)nc3)c2F)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 873697-71-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1800955 |
| ChEBI ID | — |
| PubChem CID | 11689883 |
| DrugBank | DB11816 |
| UNII ID | 2M19539ERK (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
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Trends
PubMed Central
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Additional graphs summarizing 622 documents
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Safety
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Adverse Events
Top Adverse Reactions
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6,951 adverse events reported
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