Abc-294640
Abc-294640 is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against sphingosine kinase 2.
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Trade Name
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | U07.1 | 1 | 2 | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cholangiocarcinoma | D018281 | C22.1 | — | 1 | — | — | 1 | 2 | |
| Klatskin tumor | D018285 | EFO_1001005 | — | 1 | — | — | 1 | 2 | |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | 1 | — | — | 1 | 2 |
| Prostatic neoplasms | D011471 | C61 | — | 1 | — | — | — | 1 | |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | 1 | — | — | — | 1 |
| Multiple myeloma | D009101 | C90.0 | 1 | 1 | — | — | — | 1 | |
| Large b-cell lymphoma diffuse | D016403 | C83.3 | 1 | 1 | — | — | — | 1 | |
| Kaposi sarcoma | D012514 | C46 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | — | — | — | 1 |
| Neoplasms | D009369 | C80 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ABC-294640 |
| INN | opaganib |
| Description | Abc-294640 is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against sphingosine kinase 2. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | O=C(NCc1ccncc1)C12CC3CC(C1)CC(c1ccc(Cl)cc1)(C3)C2 |
Identifiers
| PDB | — |
| CAS-ID | 915385-81-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2158685 |
| ChEBI ID | — |
| PubChem CID | 11960382 |
| DrugBank | — |
| UNII ID | DRG21OQ517 (ChemIDplus, GSRS) |
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0 adverse events reported
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