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Oxacillin
Bactocill (oxacillin) is a small molecule pharmaceutical. Oxacillin was first approved as Prostaphlin on 1982-01-01. It is used to treat bacterial endocarditis, bacterial infections, bacterial meningitis, cellulitis, and osteomyelitis amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
respiratory tract diseasesD012140
nervous system diseasesD009422
urogenital diseasesD000091642
cardiovascular diseasesD002318
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Bactocill (generic drugs available since 2012-03-30, discontinued: Prostaphlin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Oxacillin sodium
Tradename
Company
Number
Date
Products
BACTOCILL IN PLASTIC CONTAINERBaxterN-050640 RX1989-10-26
2 products, RLD, RS
Show 3 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
oxacillinANDA2022-11-10
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial endocarditisEFO_1000830D004697—
bacterial infections—D001424A49
bacterial meningitisEFO_1000831D016920G00
cellulitisEFO_0003035D002481L03.90
osteomyelitisEFO_0003102D010019M86
postoperative complications—D011183—
respiratory tract infections—D012141J06.9
staphylococcal infections—D013203A49.01
urinary tract infectionsEFO_0003103D014552N39.0
wound infection—D014946—
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CF: Beta-lactamase resistant penicillins
— J01CF04: Oxacillin
HCPCS
Code
Description
J2700
Injection, oxacillin sodium, up to 250 mg
Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Postoperative painD010149G89.18———2—2
Pain managementD059408———112
Low back painD017116HP_0003419M54.5——11—2
PainD010146EFO_0003843R52———112
Colonic neoplasmsD003110C18———1—1
Rectal neoplasmsD012004———1—1
ConstipationD003248HP_0002019K59.0———1—1
Colonic diverticulosisD043963K57.30———1—1
Colonic diverticulitisD004239———1—1
IleusD045823K56.7———1—1
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Liver cirrhosisD008103EFO_0001422K74.0——1—12
Muscle crampD009120HP_0003394——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOXACILLIN
INNoxacillin
Description
Oxacillin is a penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6beta. It has a role as an antibacterial agent and an antibacterial drug. It is a conjugate acid of an oxacillin(1-).
Classification
Small molecule
Drug classpenicillins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1onc(-c2ccccc2)c1C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12
Identifiers
PDB—
CAS-ID66-79-5
RxCUI7773
ChEMBL IDCHEMBL819
ChEBI ID7809
PubChem CID6196
DrugBankDB00713
UNII IDUH95VD7V76 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 15,329 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
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575 adverse events reported
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