Oxyphencyclimine
Daricon (oxyphencyclimine) is a small molecule pharmaceutical. Oxyphencyclimine was first approved as Daricon on 1982-01-01.
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Therapeutic Areas
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Trade Name
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Oxyphencyclimine hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| DARICON | Mylan | N-011612 DISCN | 1982-01-01 | 1 products |
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Indications
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Agency Specific
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Patent Expiration
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ATC Codes
A: Alimentary tract and metabolism drugs
— A03: Drugs for functional gastrointestinal disorders
— A03A: Drugs for functional gastrointestinal disorders
— A03AA: Synthetic anticholinergics, esters with tertiary amino group for functional gastrointestinal disorders
— A03AA01: Oxyphencyclimine
— A03C: Antispasmodics in combination with psycholeptics
— A03CA: Synthetic anticholinergic agents in combination with psycholeptics
— A03CA03: Oxyphencyclimine and psycholeptics
HCPCS
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Clinical
Clinical Trials
25 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic pain | D059350 | HP_0012532 | — | — | 6 | 1 | — | 7 | |
| Opioid-related disorders | D009293 | EFO_0005611 | F11 | — | — | — | 1 | — | 1 |
| Narcotic-related disorders | D000079524 | — | — | — | 1 | — | 1 | ||
| Substance-related disorders | D019966 | EFO_0003890 | F13 | — | — | — | 1 | — | 1 |
| Healthy volunteers/patients | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | 3 | — | 2 | — | 1 | 6 |
| Postoperative pain | D010149 | G89.18 | — | — | 5 | — | — | 5 | |
| Neuralgia | D009437 | EFO_0009430 | — | — | 1 | — | 1 | 2 | |
| Acute pain | D059787 | R52 | — | — | 2 | — | — | 2 | |
| Chronic disease | D002908 | — | — | 1 | — | — | 1 | ||
| Neoplasms | D009369 | C80 | — | — | 1 | — | — | 1 | |
| Cancer pain | D000072716 | G89.3 | — | — | 1 | — | — | 1 | |
| Low back pain | D017116 | HP_0003419 | M54.5 | — | — | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Postoperative nausea and vomiting | D020250 | EFO_0004888 | — | — | — | — | 1 | 1 | |
| Nociceptive pain | D059226 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | OXYPHENCYCLIMINE |
| INN | oxyphencyclimine |
| Description | Oxyphencyclimine is a monocarboxylic acid. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CN1CCCN=C1COC(=O)C(O)(c1ccccc1)C1CCCCC1 |
Identifiers
| PDB | — |
| CAS-ID | 125-53-1 |
| RxCUI | 32698 |
| ChEMBL ID | CHEMBL1495 |
| ChEBI ID | 7868 |
| PubChem CID | 4642 |
| DrugBank | DB00383 |
| UNII ID | 4V44H1O8XI (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
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Trends
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Additional graphs summarizing 31 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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31,105 adverse events reported
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