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Oxyphenonium
Antrenyl (oxyphenonium) is a small molecule pharmaceutical. Oxyphenonium was first approved as Antrenyl on 1982-01-01. It is known to target muscarinic acetylcholine receptor M4.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Oxyphenonium bromide
Tradename
Company
Number
Date
Products
ANTRENYLNovartisN-008492 DISCN1982-01-01
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
A: Alimentary tract and metabolism drugs
— A03: Drugs for functional gastrointestinal disorders
— A03A: Drugs for functional gastrointestinal disorders
— A03AB: Synthetic anticholinergics, quaternary ammonium compounds for functional gastrointestinal disorders
— A03AB03: Oxyphenonium
— A03AB53: Oxyphenonium, combinations
HCPCS
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Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOXYPHENONIUM
INNoxyphenonium bromide
Description
Oxyphenonium bromide is an antimuscarinic drug. It is used to treat gastric and duodenal ulcers and to relieve visceral spasms.
Classification
Small molecule
Drug classquaternary ammonium derivatives; quaternary ammonium derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC[N+](C)(CC)CCOC(=O)C(O)(c1ccccc1)C1CCCCC1
Identifiers
PDB—
CAS-ID50-10-2
RxCUI42833
ChEMBL IDCHEMBL1201286
ChEBI ID—
PubChem CID5748
DrugBankDB00219
UNII IDS9421HWB3Z (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CHRM4
CHRM4
Organism
Homo sapiens
Gene name
CHRM4
Gene synonyms
NCBI Gene ID
1132
Protein name
muscarinic acetylcholine receptor M4
Protein synonyms
acetylcholine receptor, muscarinic 4
Uniprot ID
Q4VBK7
Mouse ortholog
Chrm4 (12672)
muscarinic acetylcholine receptor M4 (Q64056)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 97 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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