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Ozagrel
Ozagrel is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target thromboxane-A synthase.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cerebral infarctionD002544I63———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Sjogren's syndromeD012859EFO_0000699M35.0——3——3
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Dry eye syndromesD015352H04.12—4———4
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOZAGREL
INNozagrel
Description
Ozagrel is a member of cinnamic acids.
Classification
Small molecule
Drug classplatelet aggregation inhibitors, primarily platelet P2Y12 receptor antagonists
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=C(O)/C=C/c1ccc(Cn2ccnc2)cc1
Identifiers
PDB—
CAS-ID82571-53-7
RxCUI—
ChEMBL IDCHEMBL11662
ChEBI ID—
PubChem CID5282440
DrugBankDB12017
UNII IDL256JB984D (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
TBXAS1
TBXAS1
Organism
Homo sapiens
Gene name
TBXAS1
Gene synonyms
CYP5, CYP5A1, TXAS
NCBI Gene ID
6916
Protein name
thromboxane-A synthase
Protein synonyms
Cytochrome P450 5A1, cytochrome P450, family 5, subfamily A, polypeptide 1, Hydroperoxy icosatetraenoate dehydratase, platelet, cytochrome P450, subfamily V, thromboxane A synthase 1 (platelet), TXA synthase
Uniprot ID
Q9HD84
Mouse ortholog
Tbxas1 (21391)
thromboxane-A synthase (P97505)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 486 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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59 adverse events reported
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