Ozanezumab
Ozanezumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against reticulon-4.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
4 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Amyotrophic lateral sclerosis | D000690 | EFO_0000253 | G12.21 | 1 | 1 | — | — | — | 2 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | 1 | — | — | — | — | 1 | |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | OZANEZUMAB |
| INN | ozanezumab |
| Description | Ozanezumab (humanized mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 1310680-64-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108679 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB12891 |
| UNII ID | 123I05210W (ChemIDplus, GSRS) |
Target
Agency Approved
RTN4
RTN4
Organism
Homo sapiens
Gene name
RTN4
Gene synonyms
KIAA0886, NOGO
NCBI Gene ID
Protein name
reticulon-4
Protein synonyms
Foocen, Human NogoA, My043 protein, neurite growth inhibitor 220, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, Nogo protein, NSP, reticulon 5, Reticulon-5, RTN-x
Uniprot ID
Mouse ortholog
Rtn4 (68585)
reticulon-4 (Q99P72)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 51 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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