Palifosfamide
Palifosfamide is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Therapeutic Areas
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Trade Name
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
363 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sarcoma | D012509 | 15 | 44 | 24 | 1 | 8 | 84 | ||
Large b-cell lymphoma diffuse | D016403 | C83.3 | 11 | 17 | 3 | 1 | — | 28 | |
Non-hodgkin lymphoma | D008228 | C85.9 | 4 | 16 | 2 | 1 | 1 | 21 | |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | C91.0 | 2 | 4 | 9 | 4 | — | 17 | |
Germ cell and embryonal neoplasms | D009373 | 1 | 12 | 2 | 1 | 1 | 16 | ||
Burkitt lymphoma | D002051 | C83.7 | 1 | 5 | — | 2 | — | 7 | |
Large-cell lymphoma anaplastic | D017728 | C84.6 | 3 | 4 | — | 1 | — | 6 | |
T-cell lymphoma peripheral | D016411 | C84.9 | 3 | 1 | — | 1 | — | 4 | |
Enteropathy-associated t-cell lymphoma | D058527 | C86.2 | 1 | — | — | 1 | — | 2 | |
Mediastinal neoplasms | D008479 | C38.3 | — | — | 1 | 1 | — | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Lymphoma | D008223 | C85.9 | 9 | 36 | 7 | — | 3 | 49 | |
Neoplasms | D009369 | C80 | 17 | 8 | 3 | — | 1 | 24 | |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 7 | 13 | 5 | — | — | 19 |
Osteosarcoma | D012516 | 5 | 9 | 4 | — | 3 | 18 | ||
Leukemia | D007938 | C95 | 2 | 10 | 6 | — | 1 | 18 | |
Hodgkin disease | D006689 | C81 | 8 | 12 | 2 | — | — | 16 | |
Neuroblastoma | D009447 | EFO_0000621 | 3 | 6 | 3 | — | 1 | 12 | |
Central nervous system neoplasms | D016543 | 4 | 8 | 2 | — | — | 11 | ||
Ewing sarcoma | D012512 | EFO_0000173 | 1 | 3 | 1 | — | 4 | 9 | |
Lung neoplasms | D008175 | C34.90 | 1 | 4 | 5 | — | — | 9 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 8 | — | — | — | 8 |
B-cell lymphoma | D016393 | 3 | 3 | — | — | — | 5 | ||
Urinary bladder neoplasms | D001749 | C67 | 1 | 5 | — | — | — | 5 | |
Mantle-cell lymphoma | D020522 | C83.1 | 3 | 3 | — | — | — | 4 | |
Follicular lymphoma | D008224 | C82 | 2 | 4 | — | — | — | 4 | |
Testicular neoplasms | D013736 | C62 | 1 | 2 | — | — | — | 3 | |
Embryonal carcinoma | D018236 | — | 2 | — | — | — | 2 | ||
Brain neoplasms | D001932 | EFO_0003833 | C71 | — | 1 | — | — | 1 | 2 |
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 2 | 1 | — | — | — | 2 |
T-cell lymphoma | D016399 | 2 | 1 | — | — | — | 2 |
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Indications Without Phase
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | PALIFOSFAMIDE |
INN | palifosfamide |
Description | Isophosphamide mustard is a phosphorodiamide. |
Classification | Small molecule |
Drug class | phosphoro-derivatives; isophosphoramide mustard derivatives |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | O=P(O)(NCCCl)NCCCl |
Identifiers
PDB | — |
CAS-ID | 31645-39-3 |
RxCUI | — |
ChEMBL ID | CHEMBL889 |
ChEBI ID | 80566 |
PubChem CID | 100427 |
DrugBank | — |
UNII ID | 6A4U6NN813 (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 117 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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