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Pargyline
Eutonyl, Eutron (pargyline) is a small molecule pharmaceutical. Pargyline was first approved as Eutron on 1982-01-01. It is known to target amine oxidase [flavin-containing] B.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Methyclothiazide
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Pargyline hydrochloride
Tradename
Company
Number
Date
Products
EUTRONAbbott BiotherapeuticsN-016047 DISCN1982-01-01
1 products
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Pargyline hydrochloride
Tradename
Company
Number
Date
Products
EUTONYLAbbott BiotherapeuticsN-013448 DISCN1982-01-01
3 products
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
C: Cardiovascular system drugs
— C02: Antihypertensives
— C02K: Other antihypertensives in atc
— C02KC: Mao inhibitors, antihypertensives
— C02KC01: Pargyline
— C02L: Antihypertensives and diuretics in combination
— C02LL: Mao inhibitors and diuretics
— C02LL01: Pargyline and diuretics
HCPCS
No data
Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePARGYLINE
INNpargyline
Description
Pargyline is an aromatic amine.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C#CCN(C)Cc1ccccc1
Identifiers
PDB—
CAS-ID555-57-7
RxCUI7930
ChEMBL IDCHEMBL673
ChEBI ID7930
PubChem CID4688
DrugBankDB01626
UNII ID9MV14S8G3E (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
MAOB
MAOB
Organism
Homo sapiens
Gene name
MAOB
Gene synonyms
NCBI Gene ID
4129
Protein name
amine oxidase [flavin-containing] B
Protein synonyms
adrenalin oxidase, MAO, brain, MAO, platelet, MAO-B, Monoamine oxidase type B, tyramine oxidase
Uniprot ID
Q7Z6S2
Mouse ortholog
Maob (109731)
amine oxidase [flavin-containing] B (Q8C0B2)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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7 adverse events reported
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