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Parsaclisib
Parsaclisib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
33 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Follicular lymphomaD008224C821—1——2
Primary myelofibrosisD055728D47.4——2——2
Mantle-cell lymphomaD020522C83.1——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LymphomaD008223C85.925———7
NeoplasmsD009369C8061———6
Non-hodgkin lymphomaD008228C85.931———3
B-cell chronic lymphocytic leukemiaD015451C91.111———1
Hemolytic anemia autoimmuneD000744EFO_1001264D59.10—1———1
PemphigusD010392EFO_1000749L10—1———1
T-cell lymphoma peripheralD016411C84.911———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Large b-cell lymphoma diffuseD016403C83.33————3
Breast neoplasmsD001943EFO_0003869C502————2
Renal cell carcinomaD0022921————1
Colorectal neoplasmsD0151791————1
Pancreatic neoplasmsD010190EFO_0003860C251————1
Endometrial neoplasmsD016889EFO_00042301————1
Head and neck neoplasmsD0062581————1
Lung neoplasmsD008175C34.901————1
MelanomaD0085451————1
B-cell lymphomaD0163931————1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePARSACLISIB
INNparsaclisib
Description
Parsaclisib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform.
Classification
Small molecule
Drug classphosphatidylinositol 3-kinase (PI3K) inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCOc1c([C@H](C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(F)c1[C@@H]1CNC(=O)C1
Identifiers
PDB—
CAS-ID1426698-88-5
RxCUI—
ChEMBL IDCHEMBL4297615
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDOS7097575K (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
PIK3CD
PIK3CD
Organism
Homo sapiens
Gene name
PIK3CD
Gene synonyms
NCBI Gene ID
5293
Protein name
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Protein synonyms
p110delta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta short variant 8/20, phosphoinositide-3-kinase C, phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta, PI3-kinase p110 subunit delta, PI3Kdelta, PtdIns-3-kinase subunit p110-delta
Uniprot ID
Q5SR49
Mouse ortholog
Pik3cd (18707)
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Q8CJ28)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 157 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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33 adverse events reported
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