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Penbutolol
Levatol (penbutolol) is a small molecule pharmaceutical. Penbutolol was first approved as Levatol on 1987-12-30. It is used to treat angina pectoris, hypertension, and myocardial infarction in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Penbutolol sulfate
Tradename
Company
Number
Date
Products
LEVATOLAuxilium PharmaceuticalsN-018976 DISCN1987-12-30
2 products, RLD
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
angina pectorisEFO_0003913D000787I20
hypertensionEFO_0000537D006973I10
myocardial infarctionEFO_0000612D009203I21
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C07: Beta-adrenergic blocking agents
— C07A: Beta blocking agents
— C07AA: Beta blocking agents, non-selective
— C07AA23: Penbutolol
— C07C: Beta blocking agents and other diuretics
— C07CA: Beta blocking agents, non-selective, and other diuretics
— C07CA23: Penbutolol and other diuretics
HCPCS
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cocaine-related disordersD019970F14—2———2
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bariatric surgeryD050110————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePENBUTOLOL
INNpenbutolol
Description
Penbutolol is a member of ethanolamines.
Classification
Small molecule
Drug classbeta-blockers (propranolol type)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(C)(C)NC[C@H](O)COc1ccccc1C1CCCC1
Identifiers
PDB—
CAS-ID38363-40-5
RxCUI7973
ChEMBL IDCHEMBL1290
ChEBI ID7954
PubChem CID37464
DrugBankDB01359
UNII ID78W62V43DY (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 259 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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60 adverse events reported
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