Benzylpenicillin
Benzylpenicillin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CE: Beta-lactamase sensitive penicillins
— J01CE01: Benzylpenicillin
— J01CE08: Benzathine benzylpenicillin
— J01CE09: Procaine benzylpenicillin
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA14: Benzylpenicillin
HCPCS
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Clinical
Clinical Trials
29 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Syphilis | D013587 | EFO_0007504 | A53.9 | 1 | 2 | 2 | 5 | — | 9 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | 1 | — | 2 | |
| Staphylococcus aureus | D013211 | NCBITaxon_1280 | — | — | — | 1 | — | 1 | |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pneumonia | D011014 | EFO_0003106 | J18 | — | — | 2 | — | 1 | 3 |
| Sepsis | D018805 | A41.9 | — | — | 2 | — | — | 2 | |
| Yaws | D015001 | EFO_0007548 | A66 | — | — | 1 | — | — | 1 |
| Treponemal infections | D014211 | EFO_1001217 | — | — | 1 | — | — | 1 | |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | 1 | — | — | 1 |
| Microbial drug resistance | D004352 | — | — | 1 | — | — | 1 | ||
| Endocarditis | D004696 | EFO_0000465 | I33 | — | — | 1 | — | — | 1 |
| Bacterial infections | D001424 | A49 | — | — | 1 | — | — | 1 | |
| Neonatal sepsis | D000071074 | HP_0040187 | — | — | 1 | — | — | 1 | |
| Hiv | D006678 | O98.7 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Rheumatic heart disease | D012214 | EFO_1001161 | I09.9 | — | 2 | — | — | 1 | 3 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 1 | — | — | — | 1 |
| Psoriasis | D011565 | EFO_0000676 | L40 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 2 | — | — | — | — | 2 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | — | — | 1 | 1 |
| Neurosyphilis | D009494 | EFO_0007339 | A50.4 | — | — | — | — | 1 | 1 |
| Tonsillitis | D014069 | HP_0011110 | J03 | — | — | — | — | 1 | 1 |
| Streptococcal infections | D013290 | EFO_1001476 | — | — | — | — | 1 | 1 | |
| Pharyngitis | D010612 | R07.0 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | BENZYLPENICILLIN |
| INN | benzylpenicillin |
| Description | Benzylpenicillin is a penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group. It has a role as an antibacterial drug, an epitope and a drug allergen. It is a penicillin allergen and a penicillin. It is a conjugate acid of a benzylpenicillin(1-). |
| Classification | Small molecule |
| Drug class | penicillins |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 61-33-6 |
| RxCUI | 7980 |
| ChEMBL ID | CHEMBL29 |
| ChEBI ID | 18208 |
| PubChem CID | 5904 |
| DrugBank | DB01053 |
| UNII ID | Q42T66VG0C (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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4,948 adverse events reported
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