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Pentolinium
Ansolysen (pentolinium) is a small molecule pharmaceutical. Pentolinium was first approved as Ansolysen on 1982-01-01.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Pentolinium tartrate
Tradename
Company
Number
Date
Products
ANSOLYSENWyethN-009372 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Traumatic brain injuriesD000070642S06——1——1
Status epilepticusD013226EFO_0008526G41——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Substance-related disordersD019966EFO_0003890F1311———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Heart diseasesD006331EFO_0003777I51.91————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePENTOLINIUM
INNpentolonium tartrate
Description
Pentolinium ion is a dication whose structure comprises a pentane backbone linking two 1-methylpyrrolidinium groups; a nicotinic antagonist used as a ganglionic blocking agent in hypertension. It contains a pyrrolidinium ion.
Classification
Small molecule
Drug classquaternary ammonium derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1
Identifiers
PDB—
CAS-ID144-44-5
RxCUI—
ChEMBL IDCHEMBL1271
ChEBI ID347401
PubChem CID5850
DrugBankDB01090
UNII ID953357GACY (ChemIDplus, GSRS)
Target
Agency Approved
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Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 584 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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413 adverse events reported
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