Pepinemab
Pepinemab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against semaphorin-4D.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
13 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Squamous cell carcinoma of head and neck | D000077195 | 1 | — | — | — | — | 1 | ||
| Melanoma | D008545 | 1 | — | — | — | — | 1 | ||
| Colorectal neoplasms | D015179 | 1 | — | — | — | — | 1 | ||
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | 1 | — | — | — | — | 1 |
| Neoplasms | D009369 | C80 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PEPINEMAB |
| INN | pepinemab |
| Description | Pepinemab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against semaphorin-4D. |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297884 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | BPZ4A29SYE (ChemIDplus, GSRS) |
Target
Agency Approved
SEMA4D
SEMA4D
Organism
Homo sapiens
Gene name
SEMA4D
Gene synonyms
C9orf164, CD100, SEMAJ
NCBI Gene ID
Protein name
semaphorin-4D
Protein synonyms
A8, BB18, CD100, GR3, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D
Uniprot ID
Mouse ortholog
Sema4d (20354)
semaphorin-4D (Q6GTM9)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 60 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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