Perflubutane
Perflubutane is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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Clinical
Clinical Trials
32 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | 1 | 1 | 1 | — | 3 |
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | — | — | 1 | 1 | — | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | — | 1 | — | 3 | 4 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | 1 | — | 2 | 3 |
| Coronary artery disease | D003324 | I25.1 | — | — | 3 | — | — | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | EFO_0003144 | I50 | 1 | 1 | — | — | — | 2 |
| Pancreatic ductal carcinoma | D021441 | 1 | 1 | — | — | — | 1 | ||
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | — | — | — | 1 |
| Blood pressure | D001794 | EFO_0004325 | — | 1 | — | — | — | 1 | |
| Cardiac catheterization | D006328 | — | 1 | — | — | — | 1 | ||
| Echocardiography | D004452 | — | 1 | — | — | — | 1 | ||
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 1 | — | — | — | 1 |
| Peripheral arterial disease | D058729 | EFO_0004265 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 | ||
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | 1 | — | — | — | — | 1 |
| Melanoma | D008545 | 1 | — | — | — | — | 1 | ||
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 1 | — | — | — | — | 1 |
| Uterine cervical neoplasms | D002583 | 1 | — | — | — | — | 1 | ||
| Vaginal neoplasms | D014625 | C52 | 1 | — | — | — | — | 1 | |
| Vulvar neoplasms | D014846 | C51 | 1 | — | — | — | — | 1 |
Indications Without Phase
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PERFLUBUTANE |
| INN | perflubutane |
| Description | Perflubutane is a fluorocarbon that is butane in which all of the hydrogens have been replaced by fluorines. Microbubbles of preflubutane are used in the ultrasound contrast agent BR14. It has a role as an ultrasound contrast agent. It is a gas molecular entity, a fluorocarbon and a fluoroalkane. |
| Classification | Small molecule |
| Drug class | blood substitutes and/or diagnostics (perfluorochemicals) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | FC(F)(F)C(F)(F)C(F)(F)C(F)(F)F |
Identifiers
| PDB | — |
| CAS-ID | 355-25-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2104979 |
| ChEBI ID | — |
| PubChem CID | 9638 |
| DrugBank | DB12821 |
| UNII ID | SE4TWR0K2C (ChemIDplus, GSRS) |
Target
Agency Approved
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Variants
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Trends
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Safety
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Adverse Events
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2 adverse events reported
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