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Phosphoric acid
Aminosyn, Freamine, Procalamine (phosphoric acid) is a small molecule pharmaceutical. Phosphoric acid was first approved as Freamine 8.5% on 1982-01-01. It is known to target lysophosphatidic acid receptor 2.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Amino acids
Tradename
Company
Number
Date
Products
AMINOSYN 3.5% IN PLASTIC CONTAINERAbbott BiotherapeuticsN-018804 DISCN1984-05-15
1 products
AMINOSYN 3.5% IN PLASTIC CONTAINERAbbott BiotherapeuticsN-018875 DISCN1984-08-08
1 products
FREAMINE HBC 6.9%B. Braun MedicalN-016822 DISCN1983-05-17
1 products
FREAMINE 8.5%B. Braun MedicalN-016822 DISCN1982-01-01
1 products
FREAMINE II 8.5%B. Braun MedicalN-016822 DISCN1982-01-01
1 products
FREAMINE III 8.5%B. Braun MedicalN-016822 DISCN1982-01-01
1 products
FREAMINE III 10%B. Braun MedicalN-016822 DISCN1982-01-01
1 products
AMINOSYN 3.5%ICU MedicalN-017789 DISCN1982-01-01
1 products
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Amino acids
+
Calcium acetate
+
Glycerin
+
Magnesium acetate
+
Phosphoric acid
+
Potassium chloride
+
Sodium acetate
+
Sodium chloride
Tradename
Company
Number
Date
Products
PROCALAMINEB. Braun MedicalN-018582 DISCN1982-05-08
1 products
Hide discontinued
Amino acids
+
Magnesium acetate
+
Phosphoric acid
+
Potassium acetate
+
Potassium chloride
+
Sodium acetate
Tradename
Company
Number
Date
Products
FREAMINE III 8.5% W/ ELECTROLYTESB. Braun MedicalN-016822 DISCN1988-07-01
1 products
Hide discontinued
Amino acids
+
Magnesium acetate
+
Phosphoric acid
+
Potassium acetate
+
Sodium chloride
Tradename
Company
Number
Date
Products
AMINOSYN 3.5% M IN PLASTIC CONTAINERAbbott BiotherapeuticsN-018804 DISCN1984-05-15
1 products
AMINOSYN 3.5% M IN PLASTIC CONTAINERAbbott BiotherapeuticsN-018875 DISCN1984-08-08
1 products
AMINOSYN 3.5% MICU MedicalN-017789 DISCN1982-01-01
1 products
Hide discontinued
Amino acids
+
Magnesium acetate
+
Phosphoric acid
+
Potassium chloride
+
Sodium acetate
+
Sodium chloride
Tradename
Company
Number
Date
Products
FREAMINE III 3% W/ ELECTROLYTESB. Braun MedicalN-016822 DISCN1982-01-01
1 products
Hide discontinued
Amino acids
+
Magnesium acetate
+
Potassium acetate
+
Sodium chloride
Tradename
Company
Number
Date
Products
AMINOSYN 3.5% MICU MedicalN-017789 DISCN1982-01-01
1 products
Hide discontinued
Amino acids
+
Magnesium chloride
+
Potassium phosphate
+
dibasic
+
Sodium chloride
Tradename
Company
Number
Date
Products
AMINOSYN 7% W/ ELECTROLYTESICU MedicalN-017789 DISCN1982-01-01
1 products
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
aminosyn-pfNew Drug Application2021-09-21
freamine iiiNew Drug Application2020-11-22
good neighbor anti nauseaunapproved drug other2023-06-19
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
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Patent Expiration
No data
ATC Codes
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HCPCS
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Clinical
Clinical Trials
43 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—10——1—11
Respiratory tract infectionsD012141J06.9—131—4
BronchitisD001991J40———123
AsthmaD001249EFO_0000270J45———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CoughD003371HP_0012735R051—2—14
Peripheral arterial diseaseD058729EFO_0004265——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hiv infectionsD015658EFO_0000764B20—1——12
NeuralgiaD009437EFO_0009430—1———1
SinusitisD012852EFO_0007486J32—1———1
Common coldD003139EFO_0007214J00—1———1
Communicable diseasesD003141—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic hyperplasiaD011470EFO_0000284N402————2
Therapeutic equivalencyD0138101————1
Mucociliary clearanceD0090791————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PneumoniaD011014EFO_0003106J18————11
Lung diseasesD008171EFO_0003818J98.4————11
Pulmonary fibrosisD011658J84.10————11
Back painD001416HP_0003418M54————11
InfectionsD007239EFO_0000544————11
IleusD045823K56.7————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePHOSPHORIC ACID
INN—
Description
Phosphoric acid is a phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom. It has a role as a solvent, a human metabolite, an algal metabolite and a fertilizer. It is a conjugate acid of a dihydrogenphosphate and a phosphate ion.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=P(O)(O)O
Identifiers
PDB—
CAS-ID7664-38-2
RxCUI8259
ChEMBL IDCHEMBL1187
ChEBI ID26078
PubChem CID1004
DrugBankDB09394
UNII ID—
Target
Agency Approved
No data
Alternate
LPAR2
LPAR2
Organism
Homo sapiens
Gene name
LPAR2
Gene synonyms
EDG4, LPA2
NCBI Gene ID
9170
Protein name
lysophosphatidic acid receptor 2
Protein synonyms
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4, G protein-coupled receptor, LPA receptor 2, LPA receptor EDG4, Lysophosphatidic acid receptor Edg-4, lysophosphatidic acid receptor EDG4
Uniprot ID
Q9HBW0
Mouse ortholog
Lpar2 (53978)
lysophosphatidic acid receptor 2 (Q9JL06)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 57,382 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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887 adverse events reported
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