Piclozotan
Piclozotan is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
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Indications
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 1 | — | — | — | 1 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PICLOZOTAN |
| INN | piclozotan |
| Description | Piclozotan (SUN-N4057) is a selective 5-HT1A receptor partial agonist, which has neuroprotective effects in animal studies. It has been through early clinical trials in humans for treatment of acute stroke, but results have not yet been announced.
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| Classification | Small molecule |
| Drug class | 5-HT1A receptor agonists/antagonists acting primarily as neuroprotectors |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | O=C1c2ccccc2OC=C(Cl)N1CCCCN1CC=C(c2ccccn2)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 182415-09-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL345237 |
| ChEBI ID | — |
| PubChem CID | 9801640 |
| DrugBank | DB12361 |
| UNII ID | FQE44HS7AH (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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